Detailed information NTG0050460

Bioinformatically predicted

Overview

• Name: comB10
• Type: Machinery gene
• Locus tag: HCW_RS00170
• Genome accession: NC_017737
• Coordinates: 32187..33320 (-)
• Length: 377 a.a.
• NCBI ID: WP_014660209.1
• Uniprot ID: I0EK64
• Organism: Helicobacter cetorum MIT 00-7128
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 27187..38320

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HCW_RS00155 (HCW_00155)	-	28661..29590 (-)	930	WP_014660206.1	GDP-L-fucose synthase family protein	-
HCW_RS09520 (HCW_00160)	gmd	29583..30728 (-)	1146	WP_014660207.1	GDP-mannose 4,6-dehydratase	-
HCW_RS09525 (HCW_00165)	-	30738..32147 (-)	1410	WP_014660208.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
HCW_RS00170 (HCW_00170)	comB10	32187..33320 (-)	1134	WP_014660209.1	DNA type IV secretion system protein ComB10	Machinery gene
HCW_RS00175 (HCW_00175)	comB9	33317..34225 (-)	909	WP_014660210.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
HCW_RS00180 (HCW_00180)	comB8	34225..34968 (-)	744	WP_014660211.1	type IV secretion system protein	Machinery gene
HCW_RS09530 (HCW_00185)	comB7	34965..35081 (-)	117	WP_014660212.1	hypothetical protein	Machinery gene
HCW_RS00185 (HCW_00190)	comB6	35104..36153 (-)	1050	WP_014660213.1	NADH-ubiquinone oxidoreductase	Machinery gene
HCW_RS00190 (HCW_00195)	-	36165..37157 (-)	993	WP_043902703.1	DUF7488 domain-containing protein	-
HCW_RS00195 (HCW_00200)	-	37157..37450 (-)	294	WP_043902704.1	YbaB/EbfC family nucleoid-associated protein	-
HCW_RS00200 (HCW_00205)	panD	37461..37814 (-)	354	WP_014660216.1	aspartate 1-decarboxylase	-

Sequence

Protein

• Length: 377 a.a.
• Molecular weight: 42303.81 Da
• Isoelectric Point: 9.6427

>NTDB_id=50460 HCW_RS00170 WP_014660209.1 32187..33320(-) (comB10) [Helicobacter cetorum MIT 00-7128]
MNKWLKGVLIFLGGFVVIMATSLIYHKKPKAPLNNQPNLLSDDEVKYPLQDYIFAQNSNQNNENNSKDATIKALQQQLEV
ALKTLNSQKISPPKQEIPKDFTKPPTKTNYSKKDLSLEQLDLLATRITPFEESPKNYEENLIFPTDSSKGIDSFTNLKEK
DITTNENRLLRTITADKMIPAFLITPISSQIAGKVIAQVESDIFANMGKAVLIPKGSKVIGYYNNNNKMGEYRLDIVWTR
IITPHGINIMLTNAKGADIKGYNGLVGELIERNFQRYGMPLLLSTLTNGLLIGLTSALNNKGNKEDTTNFFGDYLLMQMI
RQSGTGINQVINQILRDKSKIAPIVVIREGSRVFISPNTDIFFPMPKSNEVIAEFLE

Nucleotide

• Length: 1134 bp

>NTDB_id=50460 HCW_RS00170 WP_014660209.1 32187..33320(-) (comB10) [Helicobacter cetorum MIT 00-7128]
ATGAATAAATGGCTTAAAGGGGTGCTTATTTTTTTAGGGGGTTTTGTAGTGATTATGGCTACTTCTTTAATCTATCATAA
AAAGCCAAAAGCCCCCTTAAATAATCAGCCAAATCTTTTAAGTGATGATGAGGTGAAATACCCCCTACAAGACTATATTT
TCGCTCAAAATTCAAACCAAAACAATGAGAATAACTCCAAAGACGCTACCATAAAAGCCTTACAACAACAATTAGAAGTC
GCTCTAAAAACTTTAAACTCTCAAAAAATCAGCCCCCCTAAACAAGAAATCCCAAAAGATTTCACAAAGCCTCCTACAAA
GACAAATTACTCTAAAAAAGACCTTTCTTTAGAGCAATTAGATTTATTAGCCACTCGTATAACCCCCTTTGAAGAAAGCC
CTAAAAACTATGAAGAAAACCTTATTTTTCCTACAGATTCTTCTAAAGGCATAGATAGTTTCACTAATTTGAAAGAAAAA
GACATAACCACGAATGAAAACAGGCTTTTAAGAACCATTACAGCGGATAAAATGATACCAGCCTTTTTAATCACGCCCAT
TTCTAGTCAAATCGCTGGTAAAGTCATCGCCCAAGTAGAGAGCGATATTTTTGCAAACATGGGAAAGGCTGTTTTAATTC
CTAAAGGTTCTAAAGTCATAGGCTACTACAATAACAATAACAAAATGGGGGAGTATCGCCTAGATATTGTATGGACTAGA
ATTATCACACCCCATGGCATAAATATCATGCTCACTAACGCTAAAGGAGCGGATATTAAGGGCTATAATGGCTTAGTAGG
CGAACTCATTGAAAGGAATTTCCAACGCTATGGCATGCCCTTACTTCTTTCTACGCTCACTAATGGCTTATTGATAGGCT
TAACTTCCGCTTTAAACAATAAGGGCAATAAAGAAGACACAACGAATTTCTTTGGGGATTATCTCCTAATGCAAATGATA
AGACAAAGTGGCACAGGTATCAATCAAGTGATTAATCAAATTTTAAGAGATAAGAGCAAAATCGCCCCCATTGTAGTGAT
TAGAGAAGGGAGTAGAGTATTTATCTCGCCAAATACGGACATCTTTTTTCCTATGCCAAAAAGTAATGAAGTCATCGCTG
AGTTTTTGGAGTAG

Domains

Predicted by InterproScan.

• Bacterial conjugation TrbI-like protein (TrbI) (172-363)

3D structure

• AlphaFold DB: I0EK64

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB10	Helicobacter pylori P1	81.003	100	0.814