Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   ISP08_RS06520 Genome accession   NZ_CP064056
Coordinates   1334227..1334535 (+) Length   102 a.a.
NCBI ID   WP_195718091.1    Uniprot ID   A0A7T1F8U5
Organism   Staphylococcus lloydii strain 23_2_7_LY     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1329227..1339535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ISP08_RS06490 (ISP08_06490) - 1330016..1330216 (+) 201 WP_195718086.1 YqgQ family protein -
  ISP08_RS06495 (ISP08_06495) - 1330217..1331203 (+) 987 WP_195718087.1 glucokinase -
  ISP08_RS06500 (ISP08_06500) - 1331203..1331541 (+) 339 WP_195718088.1 MTH1187 family thiamine-binding protein -
  ISP08_RS06505 (ISP08_06505) - 1331528..1332151 (+) 624 WP_195718089.1 MBL fold metallo-hydrolase -
  ISP08_RS06510 (ISP08_06510) comGA 1332200..1333174 (+) 975 WP_195718090.1 competence type IV pilus ATPase ComGA Machinery gene
  ISP08_RS06515 (ISP08_06515) comGB 1333146..1334213 (+) 1068 WP_244138694.1 competence type IV pilus assembly protein ComGB -
  ISP08_RS06520 (ISP08_06520) comGC 1334227..1334535 (+) 309 WP_195718091.1 competence type IV pilus major pilin ComGC Machinery gene
  ISP08_RS06525 (ISP08_06525) comGD 1334516..1334956 (+) 441 WP_244138695.1 competence type IV pilus minor pilin ComGD -
  ISP08_RS06530 (ISP08_06530) - 1334943..1335248 (+) 306 WP_195718093.1 hypothetical protein -
  ISP08_RS06535 (ISP08_06535) - 1335241..1335636 (+) 396 WP_195718094.1 ComGF family competence protein -
  ISP08_RS06540 (ISP08_06540) - 1335804..1336316 (+) 513 WP_195718095.1 shikimate kinase -
  ISP08_RS06545 (ISP08_06545) gcvT 1336482..1337573 (+) 1092 WP_195718096.1 glycine cleavage system aminomethyltransferase GcvT -
  ISP08_RS06550 (ISP08_06550) gcvPA 1337592..1338944 (+) 1353 WP_195718097.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 102 a.a.        Molecular weight: 11265.37 Da        Isoelectric Point: 9.9951

>NTDB_id=498846 ISP08_RS06520 WP_195718091.1 1334227..1334535(+) (comGC) [Staphylococcus lloydii strain 23_2_7_LY]
MKKIKHFKAFTLIEMLLVLLIISLLLVLIIPNISKQSKHIQSTGCKAQLKLIDSQIQAYTLKFGQPPNTIDNLVSEGFIK
DDQKSCKNGQTIAINNGEAVAS

Nucleotide


Download         Length: 309 bp        

>NTDB_id=498846 ISP08_RS06520 WP_195718091.1 1334227..1334535(+) (comGC) [Staphylococcus lloydii strain 23_2_7_LY]
ATGAAAAAAATAAAACATTTCAAGGCATTTACTTTAATAGAAATGCTTTTAGTATTACTTATAATTAGTCTTCTATTGGT
ATTAATAATTCCTAACATTTCAAAACAATCTAAACATATACAATCCACAGGCTGTAAAGCACAGTTAAAACTTATAGACA
GTCAAATACAGGCTTATACATTGAAATTTGGCCAGCCTCCAAATACGATAGATAATTTAGTAAGTGAGGGATTCATAAAA
GATGATCAAAAGTCATGTAAAAATGGCCAAACAATAGCAATTAATAACGGTGAGGCTGTTGCAAGCTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(6-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T1F8U5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus MW2

64.706

100

0.647
  comGC Staphylococcus aureus N315

64.706

100

0.647
  comYC Streptococcus gordonii str. Challis substr. CH1

40

100

0.412
  comGC Bacillus subtilis subsp. subtilis str. 168

45.652

90.196

0.412
  comYC Streptococcus mutans UA140

47.059

83.333

0.392
  comYC Streptococcus mutans UA159

47.059

83.333

0.392
  comGC/cglC Streptococcus mitis SK321

38.835

100

0.392
  comGC/cglC Streptococcus mitis NCTC 12261

36.449

100

0.382