Detailed information NTG0049834

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SSUA7_RS04315
• Genome accession: NC_017622
• Coordinates: 878628..879470 (-)
• Length: 280 a.a.
• NCBI ID: WP_014638936.1
• Uniprot ID: A0A116MH00
• Organism: Streptococcus suis A7
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 873628..884470

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUA7_RS04295 (SSUA7_0837)	-	874128..874877 (-)	750	WP_014638934.1	HAD family hydrolase	-
SSUA7_RS04300 (SSUA7_0838)	rplL	875002..875367 (-)	366	WP_002936483.1	50S ribosomal protein L7/L12	-
SSUA7_RS04305 (SSUA7_0839)	rplJ	875433..875927 (-)	495	WP_002936486.1	50S ribosomal protein L10	-
SSUA7_RS04310 (SSUA7_0840)	topA	876442..878535 (-)	2094	WP_014638935.1	type I DNA topoisomerase	-
SSUA7_RS04315 (SSUA7_0841)	dprA	878628..879470 (-)	843	WP_014638936.1	DNA-processing protein DprA	Machinery gene
SSUA7_RS04320 (SSUA7_0842)	-	879531..880088 (-)	558	WP_014638937.1	sugar O-acetyltransferase	-
SSUA7_RS04325 (SSUA7_0843)	-	880217..880528 (+)	312	WP_014638938.1	rhodanese-like domain-containing protein	-
SSUA7_RS04330 (SSUA7_0844)	-	880625..881176 (+)	552	WP_014638939.1	DUF1836 domain-containing protein	-
SSUA7_RS04335 (SSUA7_0845)	trhA	881166..881816 (+)	651	WP_014638940.1	PAQR family membrane homeostasis protein TrhA	-
SSUA7_RS04340 (SSUA7_0846)	-	881849..882859 (-)	1011	WP_014638941.1	YdcF family protein	-
SSUA7_RS04345 (SSUA7_0847)	-	882856..883635 (-)	780	WP_014638942.1	ribonuclease HII	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31347.20 Da
• Isoelectric Point: 8.2214

>NTDB_id=49834 SSUA7_RS04315 WP_014638936.1 878628..879470(-) (dprA) [Streptococcus suis A7]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGIQSVQKIIKELSNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDKIYPKENRELQTYIGKHHLVLTEYEPDADPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide

• Length: 843 bp

>NTDB_id=49834 SSUA7_RS04315 WP_014638936.1 878628..879470(-) (dprA) [Streptococcus suis A7]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCAGGTTTGACCAATCTTAATGTGAATAAAGTTTTGGCCTATCAAGA
AAAACACGGAAAAAAATTGACCTTGCGAAATGTCGCTGTAGTATCTGAATGTAAAAATCCAGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
CTGGCGCTCAAACAGATTTACAATCCACCTGTACTTTTGTTTTACCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAATGGTATCCAATCTGTTCAGAAAATTATCAAAGAATTGAGCAATCGTT
TTGTCATTGTTAGTGGTTTGGCAAGAGGAATTGATACAGCAGCCCACATCGCCAGTTTGAAAAATGGAGGCCAAACCATT
GCCGTTATTGGAACAGGTTTGGATAAGATTTATCCCAAAGAAAACAGAGAATTGCAGACCTACATAGGTAAACACCATTT
AGTTTTGACTGAATATGAACCAGATGCAGACCCTCTCAAATACCATTTTCCAGAACGCAATCGCATTATAGCTGGTTTGG
TAGAAGGATTGGTAGTCTGTGAGGCAAAAATGCGGTCTGGTAGCTTGATTACCTGCGAACGTGCCTTGGAAGAAGGCAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGAGCAAAGTG
CGTTACATCAGGCTTGGACATCATTTCTGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

3D structure

• AlphaFold DB: A0A116MH00

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	69.643	100	0.696
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	62.857	100	0.629
dprA/cilB/dalA	Streptococcus pneumoniae D39	62.857	100	0.629
dprA/cilB/dalA	Streptococcus pneumoniae R6	62.857	100	0.629
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	62.857	100	0.629
dprA/cilB/dalA	Streptococcus mitis SK321	62.857	100	0.629
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.857	100	0.629
dprA	Lactococcus lactis subsp. cremoris KW2	60	100	0.6
dprA	Legionella pneumophila strain ERS1305867	42.105	88.214	0.371
dprA	Bacillus subtilis subsp. subtilis str. 168	51.244	71.786	0.368