Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   KIL00_RS21655 Genome accession   NZ_CP075344
Coordinates   4147080..4148282 (-) Length   400 a.a.
NCBI ID   WP_014481472.1    Uniprot ID   -
Organism   Bacillus subtilis subsp. subtilis strain A1 - Midalam     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4142080..4153282
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KIL00_RS21630 (KIL00_21630) rocE 4142191..4143594 (-) 1404 WP_014481465.1 amino acid permease -
  KIL00_RS21635 (KIL00_21635) rocD 4143817..4145022 (-) 1206 WP_033882007.1 ornithine aminotransferase -
  KIL00_RS21640 (KIL00_21640) rocR 4145260..4146645 (+) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  KIL00_RS21645 (KIL00_21645) - 4146627..4146815 (-) 189 Protein_4228 ATP-binding protein -
  KIL00_RS21650 (KIL00_21650) - 4146932..4147060 (-) 129 WP_213783517.1 hypothetical protein -
  KIL00_RS21655 (KIL00_21655) htrA 4147080..4148282 (-) 1203 WP_014481472.1 serine protease HtrC Regulator
  KIL00_RS21660 (KIL00_21660) vicX 4148364..4149158 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  KIL00_RS21665 (KIL00_21665) walI 4149180..4150022 (-) 843 WP_014481473.1 WalRK two-component regulatory system regulator WalI -
  KIL00_RS21670 (KIL00_21670) walH 4150009..4151376 (-) 1368 WP_014481474.1 WalRK two-component regulatory system regulator WalH -
  KIL00_RS21675 (KIL00_21675) walK 4151366..4153201 (-) 1836 WP_213783518.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42761.51 Da        Isoelectric Point: 5.1904

>NTDB_id=497861 KIL00_RS21655 WP_014481472.1 4147080..4148282(-) (htrA) [Bacillus subtilis subsp. subtilis strain A1 - Midalam]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDNSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGVVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=497861 KIL00_RS21655 WP_014481472.1 4147080..4148282(-) (htrA) [Bacillus subtilis subsp. subtilis strain A1 - Midalam]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACAACTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGTTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGCGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAATGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGTGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCAGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(231-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.264

96.5

0.417
  htrA Streptococcus pneumoniae TIGR4

45.455

82.5

0.375
  htrA Streptococcus pneumoniae D39

45.455

82.5

0.375
  htrA Streptococcus pneumoniae Rx1

45.455

82.5

0.375
  htrA Streptococcus pneumoniae R6

45.455

82.5

0.375