Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SSUD12_RS03110 Genome accession   NC_017621
Coordinates   603785..604489 (+) Length   234 a.a.
NCBI ID   WP_002935840.1    Uniprot ID   A0A0M9FML3
Organism   Streptococcus suis D12     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 598785..609489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUD12_RS03090 (SSUD12_0591) - 600593..601252 (-) 660 WP_014637676.1 amino acid ABC transporter permease -
  SSUD12_RS03095 (SSUD12_0592) - 601267..601965 (-) 699 WP_014637677.1 amino acid ABC transporter permease -
  SSUD12_RS03100 (SSUD12_0593) - 601980..602819 (-) 840 WP_014637678.1 transporter substrate-binding domain-containing protein -
  SSUD12_RS03105 (SSUD12_0594) - 602830..603591 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  SSUD12_RS03110 (SSUD12_0595) micA 603785..604489 (+) 705 WP_002935840.1 response regulator YycF Regulator
  SSUD12_RS03115 (SSUD12_0596) micB 604482..605831 (+) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SSUD12_RS03120 (SSUD12_0597) vicX 605838..606641 (+) 804 WP_014637679.1 MBL fold metallo-hydrolase Regulator
  SSUD12_RS10995 (SSUD12_0598) vga(F) 606899..608284 (+) 1386 WP_014637680.1 ABC-F type ribosomal protection protein Vga(F) -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26751.75 Da        Isoelectric Point: 4.8957

>NTDB_id=49780 SSUD12_RS03110 WP_002935840.1 603785..604489(+) (micA) [Streptococcus suis D12]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=49780 SSUD12_RS03110 WP_002935840.1 603785..604489(+) (micA) [Streptococcus suis D12]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGCCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTAGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

99.573

0.812
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment