Detailed information NTG0049736

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SSUD9_RS04075
• Genome accession: NC_017620
• Coordinates: 827147..829384 (+)
• Length: 745 a.a.
• NCBI ID: WP_014636902.1
• Uniprot ID: -
• Organism: Streptococcus suis D9
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 822147..834384

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUD9_RS04050 (SSUD9_0817)	-	822237..823166 (-)	930	WP_002937175.1	ABC transporter substrate-binding protein	-
SSUD9_RS04055 (SSUD9_0818)	-	823179..823964 (-)	786	WP_014636900.1	ABC transporter ATP-binding protein	-
SSUD9_RS04060 (SSUD9_0819)	-	824116..825541 (-)	1426	Protein_755	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
SSUD9_RS04065 (SSUD9_0821)	-	825688..826434 (+)	747	WP_014636901.1	lysophospholipid acyltransferase family protein	-
SSUD9_RS04070 (SSUD9_0822)	comEA/celA/cilE	826501..827163 (+)	663	WP_002935348.1	helix-hairpin-helix domain-containing protein	Machinery gene
SSUD9_RS04075 (SSUD9_0823)	comEC/celB	827147..829384 (+)	2238	WP_014636902.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SSUD9_RS11430 (SSUD9_0824)	-	829386..829529 (+)	144	WP_002935351.1	transposase	-
SSUD9_RS04085 (SSUD9_0826)	-	829708..830364 (+)	657	WP_002935353.1	CBS domain-containing protein	-
SSUD9_RS04090 (SSUD9_0827)	-	830649..831938 (-)	1290	WP_014636903.1	IS4-like element ISSsu2 family transposase	-
SSUD9_RS04095 (SSUD9_0828)	-	832017..832798 (+)	782	Protein_762	hypothetical protein	-
SSUD9_RS04100 (SSUD9_0829)	-	832804..834075 (+)	1272	WP_002935355.1	toxic anion resistance protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84269.21 Da
• Isoelectric Point: 7.3958

>NTDB_id=49736 SSUD9_RS04075 WP_014636902.1 827147..829384(+) (comEC/celB) [Streptococcus suis D9]
MSRLSKLPCQPVHLAVLAVAAYFAVHSFSLLTMGLLSLLLLVFGFRQGKAVFIKTLPLLALCGLFFGYQKVQWERADQLA
PEQVTTMQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLTSQEEQTYFQKLTGLVQLEVEAEISLPAGQRNFKGFDYQAYL
KTQGIYRTVKITAIKKIVPVQSWNVFDWLSNWRRQALVYVKTNFPAPMSHYMTGLLFGELDSEFDQMSDLYSSLGIIHLF
ALSGMQVGFVIDKFRWILLRLGLTKETVDKLQIPFSLVYASLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFAFSFVFDVLLLPGLSV
IFLLSPIVKITWINGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIYVSPGSLTVPDFVATLKEINVPVHVVEVGERLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
KTNFLFTGDLEQGELDLIESYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=49736 SSUD9_RS04075 WP_014636902.1 827147..829384(+) (comEC/celB) [Streptococcus suis D9]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCGTTCACCTGGCAGTCTTGGCGGTGGCAGCTTACTTTGCAGTCCACTC
TTTTTCCCTCTTGACAATGGGCCTGCTGAGTTTGTTGTTGCTGGTCTTTGGATTTCGGCAAGGTAAGGCAGTTTTCATCA
AAACGCTGCCGCTTTTAGCCCTATGTGGTCTGTTTTTCGGATACCAAAAGGTCCAATGGGAGCGGGCAGACCAGTTAGCC
CCAGAGCAAGTGACGACTATGCAGGTCATTCCAGATACGATTGAAGTCAACGGGGATAGCCTGTCCTTCCGCGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTATAAATTAACCAGTCAGGAGGAACAGACCTATTTTCAAAAGCTGACAGGTTTGG
TCCAGCTTGAAGTGGAAGCAGAGATCAGCCTGCCAGCAGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGTATTTATCGGACGGTCAAGATTACGGCAATCAAGAAGATTGTCCCAGTCCAGTCTTGGAATGTCTTTGA
CTGGTTGTCAAACTGGCGGAGGCAGGCCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGCCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGAGTTTGACCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTGTCATCGACAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAAGAAAC
GGTTGATAAATTACAAATTCCCTTTTCCCTTGTCTATGCGAGCTTGACAGGTTTTTCCGTATCGGTGGTGCGGTCTTTGG
TTCAAAAAATTTTGGGTAATCTGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGTTGATACTG
CCCCGATTTCTGCTGACAGCTGGTGGTGTCCTGACCTTTACCTATGCTTTTTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAAAGTCTCAGTATTTCACTTGGGATTTTGCCAGTGCTCATGACCTATTTCTATG
CCTTTCAGCCCCTGTCTATCCTCTTGACCTTTGCCTTTTCTTTTGTCTTTGATGTCCTACTCTTGCCAGGCTTGTCAGTC
ATTTTTCTCCTGTCGCCAATCGTCAAGATTACTTGGATCAACGGATTTTTTGTCTTTATGGAAAAAATCATTGTCTGGGT
GGCGGATTTGGGATTGCGACCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTTTTGCTCTTGCTGGTCAGCCTCTTCT
TACTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGCGGACGAGTTGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGACACAGAC
CATGTGGGGGATGTGCTGGAAGTGGCGAAGCAGGTCCAGATTGGTCGGATTTACGTGTCGCCGGGAAGCCTGACGGTGCC
TGACTTTGTAGCCACCTTGAAAGAAATTAATGTCCCTGTTCATGTTGTTGAGGTGGGCGAACGCTTACCAATTTTTGACT
CTTACCTGGAAGTCCTTTATCCAGATGGGACAGGAGACGGTGGCAATAATGACTCCATTGTCCTTTATGGTCGCTTGCTG
AAAACTAATTTTCTCTTTACAGGGGACTTGGAGCAGGGGGAGTTGGACTTGATAGAATCTTATCCTAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGATAGTCGCAATATCCAA
GTCTATCGTACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (28-175)

• Competence protein (Competence) (215-461)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.836	99.732	0.537
comEC/celB	Streptococcus mitis NCTC 12261	52.632	99.463	0.523
comEC/celB	Streptococcus pneumoniae TIGR4	51.752	99.597	0.515
comEC/celB	Streptococcus pneumoniae Rx1	51.482	99.597	0.513
comEC/celB	Streptococcus pneumoniae D39	51.482	99.597	0.513
comEC/celB	Streptococcus pneumoniae R6	51.482	99.597	0.513
comEC	Lactococcus lactis subsp. cremoris KW2	48.594	100	0.487