Detailed information NTG0049721

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: SSUD9_RS00830
• Genome accession: NC_017620
• Coordinates: 128687..129121 (+)
• Length: 144 a.a.
• NCBI ID: WP_002936547.1
• Uniprot ID: A0A0Z8H0U1
• Organism: Streptococcus suis D9
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 123687..134121

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUD9_RS00795 (SSUD9_0133)	-	124429..124794 (+)	366	WP_002936568.1	DUF1033 family protein	-
SSUD9_RS00800 (SSUD9_0134)	-	124829..125779 (-)	951	WP_014636751.1	S66 family peptidase	-
SSUD9_RS00805 (SSUD9_0135)	comYA	125865..126815 (+)	951	WP_002936562.1	competence type IV pilus ATPase ComGA	Machinery gene
SSUD9_RS00810 (SSUD9_0136)	comYB	126727..127764 (+)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
SSUD9_RS00815 (SSUD9_0137)	comYC	127766..128047 (+)	282	WP_002936550.1	competence type IV pilus major pilin ComGC	Machinery gene
SSUD9_RS00820 (SSUD9_0138)	comGD	128028..128435 (+)	408	WP_014636753.1	competence type IV pilus minor pilin ComGD	-
SSUD9_RS00825 (SSUD9_0139)	comYE	128407..128700 (+)	294	WP_002936548.1	competence type IV pilus minor pilin ComGE	Machinery gene
SSUD9_RS00830 (SSUD9_0140)	comGF/cglF	128687..129121 (+)	435	WP_002936547.1	competence type IV pilus minor pilin ComGF	Machinery gene
SSUD9_RS00835 (SSUD9_0141)	comGG	129099..129509 (+)	411	WP_002936546.1	competence type IV pilus minor pilin ComGG	-
SSUD9_RS00840 (SSUD9_0142)	comYH	129566..130519 (+)	954	WP_014636755.1	class I SAM-dependent methyltransferase	Machinery gene
SSUD9_RS00845 (SSUD9_0143)	-	130569..131756 (+)	1188	WP_002936543.1	acetate kinase	-
SSUD9_RS00850 (SSUD9_0144)	-	132071..132622 (+)	552	WP_014636756.1	folate family ECF transporter S component	-
SSUD9_RS00855 (SSUD9_0145)	-	132676..133932 (+)	1257	WP_002936539.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16580.00 Da
• Isoelectric Point: 6.9819

>NTDB_id=49721 SSUD9_RS00830 WP_002936547.1 128687..129121(+) (comGF/cglF) [Streptococcus suis D9]
MLKSKIPAFTLLECLVALIILSGSLLVFEGLSKLLVQEAHYQGQTVQKEWLVFSSQLRLEWDQSDLVKVENGKVYVNKVE
QALAFGKSRSDDFRKTNDRGQGYQPMLYQVDSAAIYQENQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

• Length: 435 bp

>NTDB_id=49721 SSUD9_RS00830 WP_002936547.1 128687..129121(+) (comGF/cglF) [Streptococcus suis D9]
TTGTTAAAAAGTAAAATTCCTGCTTTTACTCTCTTGGAATGCTTGGTAGCTTTAATCATCCTATCAGGAAGTCTTCTGGT
CTTTGAAGGCTTGTCAAAACTGCTGGTCCAAGAAGCGCATTATCAAGGTCAGACCGTTCAAAAGGAATGGTTGGTCTTTT
CTAGCCAGTTGCGGTTGGAGTGGGACCAGTCGGACTTGGTCAAGGTTGAAAATGGCAAGGTCTATGTCAACAAAGTCGAA
CAGGCTTTGGCCTTTGGCAAGTCACGGTCGGATGATTTTCGGAAAACAAATGACAGGGGACAGGGTTACCAGCCCATGCT
CTATCAGGTGGATAGCGCAGCCATTTACCAAGAAAACCAGCTGGTGCGCATCGACTTTAGCTTTAAAAACGGAGAGGAGC
GGACCTTTATTTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

3D structure

• AlphaFold DB: A0A0Z8H0U1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	54.61	97.917	0.535
comGF/cglF	Streptococcus pneumoniae D39	54.61	97.917	0.535
comGF/cglF	Streptococcus pneumoniae R6	54.61	97.917	0.535
comGF/cglF	Streptococcus pneumoniae TIGR4	54.61	97.917	0.535
comGF/cglF	Streptococcus mitis NCTC 12261	55.224	93.056	0.514
comGF/cglF	Streptococcus mitis SK321	52.239	93.056	0.486
comYF	Streptococcus mutans UA140	48.611	100	0.486
comYF	Streptococcus mutans UA159	47.917	100	0.479
comGF	Lactococcus lactis subsp. cremoris KW2	45.39	97.917	0.444