Detailed information NTG0049495

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: SALIVA_RS09425
• Genome accession: NC_017595
• Coordinates: 2060732..2061169 (-)
• Length: 145 a.a.
• NCBI ID: WP_014635118.1
• Uniprot ID: -
• Organism: Streptococcus salivarius JIM8777
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2055732..2066169

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SALIVA_RS09390 (SALIVA_1921)	-	2055770..2056432 (-)	663	WP_014635111.1	CPBP family intramembrane glutamic endopeptidase	-
SALIVA_RS09395 (SALIVA_1922)	-	2056546..2056992 (-)	447	WP_014635112.1	hypothetical protein	-
SALIVA_RS09400 (SALIVA_1923)	-	2057070..2057726 (-)	657	WP_014635113.1	CPBP family intramembrane glutamic endopeptidase	-
SALIVA_RS09405 (SALIVA_1924)	-	2057738..2057935 (-)	198	WP_014635114.1	helix-turn-helix transcriptional regulator	-
SALIVA_RS09410 (SALIVA_1925)	-	2058186..2059379 (-)	1194	WP_014635115.1	acetate kinase	-
SALIVA_RS09415 (SALIVA_1926)	comYH	2059436..2060392 (-)	957	WP_014635116.1	class I SAM-dependent methyltransferase	Machinery gene
SALIVA_RS09420 (SALIVA_1927)	comGG	2060437..2060754 (-)	318	WP_041826709.1	competence type IV pilus minor pilin ComGG	-
SALIVA_RS09425 (SALIVA_1928)	comYF	2060732..2061169 (-)	438	WP_014635118.1	competence type IV pilus minor pilin ComGF	Machinery gene
SALIVA_RS09430 (SALIVA_1929)	comGE	2061156..2061386 (-)	231	WP_014635119.1	competence type IV pilus minor pilin ComGE	-
SALIVA_RS09435 (SALIVA_1930)	comYD	2061418..2061846 (-)	429	WP_014632541.1	competence type IV pilus minor pilin ComGD	Machinery gene
SALIVA_RS09440 (SALIVA_1931)	comYC	2061806..2062120 (-)	315	WP_037611125.1	competence type IV pilus major pilin ComGC	Machinery gene
SALIVA_RS09445 (SALIVA_1932)	comYB	2062129..2063229 (-)	1101	WP_148263031.1	competence type IV pilus assembly protein ComGB	Machinery gene
SALIVA_RS09450 (SALIVA_1933)	comGA/cglA/cilD	2063111..2064052 (-)	942	WP_002887018.1	competence type IV pilus ATPase ComGA	Machinery gene
SALIVA_RS09455 (SALIVA_1934)	-	2064132..2064494 (-)	363	WP_014635121.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16125.55 Da
• Isoelectric Point: 8.4658

>NTDB_id=49495 SALIVA_RS09425 WP_014635118.1 2060732..2061169(-) (comYF) [Streptococcus salivarius JIM8777]
MSLNSKVRAFTLLECLVALLVIAGSVQVYQGLATVLVSNVKQVKQQESQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSATDFRKTNADGRGYQPMLFNVKASTISQNNQIVTIQVTLKNGLQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=49495 SALIVA_RS09425 WP_014635118.1 2060732..2061169(-) (comYF) [Streptococcus salivarius JIM8777]
ATGTCTCTCAATAGTAAGGTTCGCGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTGATTGCTGGTTCAGTTCA
AGTTTATCAAGGTCTGGCTACAGTATTGGTGAGCAATGTTAAGCAGGTCAAGCAACAAGAAAGCCAAGACTGGCTTCTAT
TCGTTCAACAAATGGAGGCAGAATTAGAAGGTTGTCAGTTGGTAAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAAGACCTGGCTTTTGGACTTTCAAGTGCTACTGATTTTCGAAAAACAAATGCTGATGGTCGAGGCTATCAACCAAT
GCTTTTCAATGTAAAAGCTAGTACAATTAGCCAAAATAACCAGATAGTCACCATCCAAGTGACTCTTAAAAATGGGCTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	57.447	97.241	0.559
comYF	Streptococcus mutans UA159	56.738	97.241	0.552
comGF/cglF	Streptococcus pneumoniae Rx1	50	97.931	0.49
comGF/cglF	Streptococcus pneumoniae D39	50	97.931	0.49
comGF/cglF	Streptococcus pneumoniae R6	50	97.931	0.49
comGF/cglF	Streptococcus pneumoniae TIGR4	50	97.931	0.49
comGF/cglF	Streptococcus mitis NCTC 12261	47.222	99.31	0.469
comGF/cglF	Streptococcus mitis SK321	47.222	99.31	0.469
comGF	Lactococcus lactis subsp. cremoris KW2	44.604	95.862	0.428