Detailed information NTG0494146

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: IM723_RS01475
• Genome accession: NZ_CP063275
• Coordinates: 266551..267450 (+)
• Length: 299 a.a.
• NCBI ID: WP_179974221.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain DMST-H2
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 261551..272450

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IM723_RS01455	trkA	262688..264037 (-)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-
IM723_RS01460	-	264326..264835 (+)	510	WP_011680717.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
IM723_RS01465	-	265146..265703 (+)	558	WP_002949523.1	ECF transporter S component	-
IM723_RS01470	-	265706..266356 (+)	651	WP_095559229.1	phosphatase PAP2 family protein	-
IM723_RS01475	comR	266551..267450 (+)	900	WP_179974221.1	helix-turn-helix domain-containing protein	Regulator
IM723_RS09780	-	267625..268749 (+)	1125	Protein_237	cysteine peptidase family C39 domain-containing protein	-
IM723_RS01500	-	269152..269721 (+)	570	Protein_238	ATP-binding cassette domain-containing protein	-
IM723_RS01505	-	269916..270143 (+)	228	WP_232087121.1	DUF805 domain-containing protein	-
IM723_RS09790	-	270364..270711 (-)	348	WP_244810392.1	DUF4153 domain-containing protein	-
IM723_RS09795	-	271173..271544 (-)	372	WP_244810394.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35302.78 Da
• Isoelectric Point: 5.2218

>NTDB_id=494146 IM723_RS01475 WP_179974221.1 266551..267450(+) (comR) [Streptococcus thermophilus strain DMST-H2]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWQESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=494146 IM723_RS01475 WP_179974221.1 266551..267450(+) (comR) [Streptococcus thermophilus strain DMST-H2]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGCAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGAAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTATAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAAGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421