Detailed information NTG0049370

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SSAL_RS00020
• Genome accession: NC_017594
• Coordinates: 2850..4085 (-)
• Length: 411 a.a.
• NCBI ID: WP_013991347.1
• Uniprot ID: A0AB37CMH1
• Organism: Streptococcus salivarius 57.I
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1..9085

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSAL_RS00010 (Ssal_00001)	dnaA	414..1778 (-)	1365	WP_014632472.1	chromosomal replication initiator protein DnaA	-
SSAL_RS00015 (Ssal_00002)	spo0J	2017..2784 (-)	768	WP_013991348.1	ParB/RepB/Spo0J family partition protein	Regulator
SSAL_RS00020 (Ssal_00003)	htrA	2850..4085 (-)	1236	WP_013991347.1	trypsin-like peptidase domain-containing protein	Regulator
SSAL_RS00025 (Ssal_00004)	rlmH	4291..4770 (+)	480	WP_014632473.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SSAL_RS00030 (Ssal_00005)	-	4786..5469 (+)	684	WP_013991345.1	YoaK family protein	-
SSAL_RS00050 (Ssal_00006)	-	6023..8617 (-)	2595	WP_014632475.1	YfhO family protein	-

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42915.09 Da
• Isoelectric Point: 4.6266

>NTDB_id=49370 SSAL_RS00020 WP_013991347.1 2850..4085(-) (htrA) [Streptococcus salivarius 57.I]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNSTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSSQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDDVKAGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide

• Length: 1236 bp

>NTDB_id=49370 SSAL_RS00020 WP_013991347.1 2850..4085(-) (htrA) [Streptococcus salivarius 57.I]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCAATTGCAATGCTTGTTATTGGCTTGCTCGGTGGTTTGCTAGGTGC
CTTTATCCTACTAACAGCAGCAGGGGTATCTTTTACCAATTCAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ATAATACAACAGATACAACTAAAGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTACCAAGAAGGGTCA
TCTTCAGATTCTCTAAATGAACTTTATGGCCGTATCTTTGGTGGAGATGATAGTTCTGACTCTAGCCAAGACAAATCAAA
AGATTCTGATGGGTTACAAGTCGCTGGTGAAGGTTCCGGTGTTATCTACAAAAAGGATGGTAAAGAGGCTTATATCGTAA
CCAACAACCACGTTGTCGATGGCGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATTAAAACCGTAGCGGAATTTGCAGACTC
AAACTCTCTCACAGTCGGTGAGAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAGG
GAATCGTTTCTAGCCTTAGCCGTACCGTAACTATGCAAAACGACAATGGTGAAACTGTTTCAACAAATGCTATCCAAACA
GATGCTGCCATTAACCCTGGTAACTCAGGTGGTGCCTTAGTCAATATCGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCAGCAGTCGCTGGTAGCGCCGTTGAAGGTATGGGATTTGCCATTCCATCAAACGATGTTGTCGAAA
TCATCAATCAATTGGAAAAAGACGGTAAAGTTACACGACCAGCCCTAGGAATCTCAATGGCCGATCTTAACAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGATGTGAAAGCTGGAGTTGTAGTCGGCAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATCACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTGTCTGACTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (7-406)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.787	98.054	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.389	98.783	0.567
htrA	Streptococcus pneumoniae Rx1	54.279	99.513	0.54
htrA	Streptococcus pneumoniae R6	54.279	99.513	0.54
htrA	Streptococcus pneumoniae TIGR4	54.279	99.513	0.54
htrA	Streptococcus pneumoniae D39	54.279	99.513	0.54
htrA	Streptococcus mitis NCTC 12261	54.279	99.513	0.54