Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   INP95_RS00265 Genome accession   NZ_CP063117
Coordinates   55115..56338 (+) Length   407 a.a.
NCBI ID   WP_049384521.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C142_1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 50115..61338
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP95_RS00240 (INP95_00240) - 50699..51493 (-) 795 WP_070776080.1 sulfite exporter TauE/SafE family protein -
  INP95_RS00245 (INP95_00245) rppH 51493..52086 (-) 594 WP_049384519.1 RNA pyrophosphohydrolase -
  INP95_RS00250 (INP95_00250) ampD 52571..53134 (-) 564 WP_049371639.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  INP95_RS00255 (INP95_00255) pilA 53277..53720 (+) 444 WP_049369499.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  INP95_RS00260 (INP95_00260) pilB 53727..55106 (+) 1380 WP_049384520.1 GspE/PulE family protein Machinery gene
  INP95_RS00265 (INP95_00265) pilC 55115..56338 (+) 1224 WP_049384521.1 type II secretion system F family protein Machinery gene
  INP95_RS00270 (INP95_00270) pilD 56335..57012 (+) 678 WP_049384522.1 prepilin peptidase Machinery gene
  INP95_RS00275 (INP95_00275) coaE 57101..57721 (+) 621 WP_049384523.1 dephospho-CoA kinase -
  INP95_RS00280 (INP95_00280) yacG 57714..57920 (+) 207 WP_005695505.1 DNA gyrase inhibitor YacG -
  INP95_RS00285 (INP95_00285) - 57917..58198 (+) 282 WP_049384524.1 GNAT family N-acetyltransferase -
  INP95_RS00290 (INP95_00290) rhlB 58289..59548 (+) 1260 WP_070776274.1 ATP-dependent RNA helicase RhlB -
  INP95_RS00295 (INP95_00295) mreD 59589..60077 (-) 489 WP_049364929.1 rod shape-determining protein MreD -
  INP95_RS00300 (INP95_00300) mreC 60077..61141 (-) 1065 WP_197559694.1 rod shape-determining protein MreC -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 46246.91 Da        Isoelectric Point: 9.8560

>NTDB_id=493031 INP95_RS00265 WP_049384521.1 55115..56338(+) (pilC) [Haemophilus parainfluenzae strain M1C142_1]
MAKQKLFYFQAYDQRQQWQKGSLVAQSKQAAQFLLIAKGFSRIRLQQDWQLNQKPKNAEISALLNQLATLLSSAIPLKNA
LHILQDNCTQLGLHQWLGALIELIESGLPFSQSLEIQGKYLNFQEIQLIQVGEMTGKLAEVCTKIAERRTQSLALQRKLQ
KIMLYPVMVLGISLSLTLILLLFVVPQFAEMYGENSAELPTLTAVLLAMSQFLQHHFISLMIVCIFALFMLKMALKHSLW
LNQKKNTLIGRMPIWGNIICLSRLISFSHNLQLMLQSGVALTPALNSFLPKQQTWQTQRTLKGDILLQQEVRSILQWVSQ
GYPFSESVSSHLFPMEAQQMLQIGEKSGKLALMLRHIADNYQEKLNHQIDLLSQLLEPLMMLIIGSLIGIIMMGMYLPIF
NMGSVIQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=493031 INP95_RS00265 WP_049384521.1 55115..56338(+) (pilC) [Haemophilus parainfluenzae strain M1C142_1]
ATGGCAAAGCAAAAACTCTTTTATTTTCAAGCCTATGATCAGCGGCAACAATGGCAAAAAGGTAGTCTTGTTGCACAATC
TAAACAAGCTGCGCAATTTCTGTTAATTGCAAAAGGTTTTAGTAGAATTCGCTTGCAACAAGATTGGCAACTTAATCAAA
AACCGAAAAATGCAGAAATCAGTGCTTTATTGAATCAATTGGCTACTCTGCTCAGCTCTGCCATTCCATTAAAAAATGCA
TTGCATATTTTGCAAGATAACTGCACACAATTGGGATTGCATCAGTGGCTTGGTGCCTTAATTGAGTTAATTGAAAGTGG
TCTTCCGTTTTCACAAAGTTTAGAAATACAAGGAAAGTATTTAAATTTTCAAGAAATTCAGCTCATTCAGGTGGGAGAAA
TGACAGGAAAACTGGCAGAAGTATGCACTAAAATCGCAGAACGTCGAACGCAATCATTAGCGCTTCAACGCAAATTACAA
AAAATTATGCTTTATCCTGTCATGGTATTAGGTATTTCGCTTTCACTTACGTTAATTTTACTGCTTTTCGTTGTACCACA
ATTTGCTGAAATGTATGGCGAAAATTCCGCTGAATTGCCTACATTAACAGCTGTGTTATTAGCCATGTCTCAATTCCTAC
AACATCATTTTATTTCATTGATGATTGTCTGCATTTTCGCTCTTTTTATGCTGAAGATGGCATTAAAACATTCTCTTTGG
CTGAACCAAAAAAAGAATACACTGATTGGTCGCATGCCAATTTGGGGCAATATCATTTGCCTTTCTCGTTTAATCAGTTT
TAGCCATAACCTGCAATTAATGCTTCAATCAGGAGTGGCATTAACGCCTGCGTTAAATAGTTTTCTTCCCAAACAGCAAA
CTTGGCAAACACAACGTACCTTAAAAGGCGATATTCTGCTACAACAAGAAGTGCGGTCAATTTTACAGTGGGTTTCTCAA
GGCTATCCATTTTCAGAAAGTGTCAGTAGCCATCTTTTTCCAATGGAAGCGCAGCAAATGCTACAGATTGGAGAGAAAAG
TGGAAAACTTGCATTGATGTTGCGACATATTGCTGACAACTATCAAGAAAAGCTTAATCATCAAATTGATTTACTTTCCC
AACTTTTAGAGCCATTAATGATGCTCATTATTGGTAGTTTAATTGGTATCATAATGATGGGGATGTATCTGCCAATTTTT
AATATGGGTTCGGTAATCCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

69.554

99.263

0.69
  pilC Haemophilus influenzae 86-028NP

68.812

99.263

0.683
  pilC Glaesserella parasuis strain SC1401

39.9

98.526

0.393