Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   INQ00_RS00260 Genome accession   NZ_CP063110
Coordinates   52452..53675 (+) Length   407 a.a.
NCBI ID   WP_197546950.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C160_1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 47452..58675
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INQ00_RS00235 (INQ00_00235) - 48036..48830 (-) 795 WP_197546945.1 sulfite exporter TauE/SafE family protein -
  INQ00_RS00240 (INQ00_00240) rppH 48961..49423 (-) 463 Protein_47 RNA pyrophosphohydrolase -
  INQ00_RS00245 (INQ00_00245) ampD 49906..50469 (-) 564 WP_197546947.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  INQ00_RS00250 (INQ00_00250) pilA 50614..51057 (+) 444 WP_197546948.1 prepilin peptidase-dependent pilin Machinery gene
  INQ00_RS00255 (INQ00_00255) pilB 51064..52443 (+) 1380 WP_197546949.1 GspE/PulE family protein Machinery gene
  INQ00_RS00260 (INQ00_00260) pilC 52452..53675 (+) 1224 WP_197546950.1 type II secretion system F family protein Machinery gene
  INQ00_RS00265 (INQ00_00265) pilD 53672..54349 (+) 678 WP_197546951.1 prepilin peptidase Machinery gene
  INQ00_RS00270 (INQ00_00270) coaE 54436..55056 (+) 621 WP_197546952.1 dephospho-CoA kinase -
  INQ00_RS00275 (INQ00_00275) yacG 55049..55255 (+) 207 WP_197546953.1 DNA gyrase inhibitor YacG -
  INQ00_RS00280 (INQ00_00280) - 55252..55533 (+) 282 WP_197546954.1 GNAT family N-acetyltransferase -
  INQ00_RS00285 (INQ00_00285) rhlB 55624..56883 (+) 1260 WP_197546955.1 ATP-dependent RNA helicase RhlB -
  INQ00_RS00290 (INQ00_00290) mreD 56925..57413 (-) 489 WP_111327318.1 rod shape-determining protein MreD -
  INQ00_RS00295 (INQ00_00295) mreC 57413..58477 (-) 1065 WP_197546956.1 rod shape-determining protein MreC -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 46189.73 Da        Isoelectric Point: 9.7422

>NTDB_id=492875 INQ00_RS00260 WP_197546950.1 52452..53675(+) (pilC) [Haemophilus parainfluenzae strain M1C160_1]
MAKQKLFYFQAYDQRQQWQKGSLVAQSKQAAQFLLIAKGFSHIRLQQDWQLNQKPKNAEISALLNQLATLLSSAIPLKNA
LHILQDNCTQLGLHQWLSALIELIESGLPFSQSLEIQGKYLNFQEIQLIQVGEMTGKLAEVCTKIAERRTQSLTLQRKLQ
KIMLYPAMVLGISLSLTLILLLFVVPQFAEMYGENSAELPTLTAVLLAMSQFLQHHFVALMIACTFAIFMLKMALKHSLW
LNQKKNALISRMPIWGNIICLSRLISFSHNLQLMLQSGVALTPALNSFLPKQQTWQTQRTLKGDILLQQEVRSILQWVSQ
GYPFSESVSSHLFPMEAQQMLQIGEKSGKLALMLRHIADNYQEKLNHQIDLLSQLLEPLMMLIIGSLIGIIMMGMYLPIF
NMGSVIQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=492875 INQ00_RS00260 WP_197546950.1 52452..53675(+) (pilC) [Haemophilus parainfluenzae strain M1C160_1]
ATGGCAAAACAAAAACTCTTTTACTTCCAAGCCTATGATCAGCGGCAACAATGGCAAAAAGGTAGCCTTGTTGCTCAATC
TAAACAAGCCGCACAATTTCTGTTAATTGCAAAAGGTTTTAGTCACATTCGCTTGCAACAAGATTGGCAACTTAATCAGA
AACCGAAAAATGCAGAAATCAGTGCTTTATTGAATCAACTGGCTACATTGCTCAGTTCTGCCATTCCATTAAAAAATGCA
TTACATATTTTGCAAGACAACTGCACACAATTGGGTTTGCATCAGTGGCTTAGCGCCTTAATTGAGTTAATTGAAAGTGG
TCTTCCGTTTTCACAAAGCTTGGAAATACAAGGAAAGTATTTAAACTTTCAAGAGATTCAACTTATTCAAGTGGGAGAAA
TGACAGGAAAACTGGCAGAGGTATGCACTAAAATTGCAGAACGTCGAACACAATCATTAACGCTTCAACGCAAATTGCAA
AAAATTATGCTTTATCCTGCCATGGTATTAGGTATTTCGCTTTCACTTACGTTGATTTTATTACTCTTCGTTGTACCGCA
ATTTGCTGAAATGTATGGCGAAAATTCCGCTGAATTGCCTACATTGACTGCTGTGTTATTAGCCATGTCTCAATTCCTAC
AACATCATTTTGTTGCGTTAATGATTGCCTGCACTTTCGCTATTTTTATGTTGAAGATGGCATTAAAACATTCCCTTTGG
CTAAATCAAAAAAAGAATGCACTAATTAGCCGCATGCCAATTTGGGGCAATATCATTTGCCTTTCTCGCCTAATCAGTTT
TAGCCATAACCTCCAATTAATGCTTCAATCCGGAGTGGCATTAACGCCAGCCTTAAATAGCTTCCTCCCCAAACAACAAA
CCTGGCAAACACAACGTACCTTAAAAGGTGATATTCTGCTACAACAAGAAGTGCGGTCAATTTTACAGTGGGTTTCGCAA
GGTTATCCATTTTCAGAAAGTGTCAGTAGTCATCTTTTCCCAATGGAAGCACAACAAATGCTACAGATTGGAGAAAAAAG
TGGAAAACTTGCGTTGATGTTGCGTCATATTGCTGATAACTATCAAGAAAAGCTCAATCATCAAATTGATTTACTTTCCC
AACTTTTAGAGCCTTTAATGATGCTCATCATTGGTAGTTTAATCGGTATTATTATGATGGGCATGTATCTGCCGATTTTT
AATATGGGATCCGTAATCCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

69.802

99.263

0.693
  pilC Haemophilus influenzae 86-028NP

69.059

99.263

0.685
  pilC Glaesserella parasuis strain SC1401

39.9

98.526

0.393