Detailed information NTG0049240

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: SPNOXC_RS06105
• Genome accession: NC_017592
• Coordinates: 1160456..1161304 (-)
• Length: 282 a.a.
• NCBI ID: WP_000705300.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae OXC141
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1155456..1166304

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPNOXC_RS06090 (SPNOXC11280)	-	1155697..1156056 (-)	360	WP_001237219.1	YbaN family protein	-
SPNOXC_RS06095 (SPNOXC11290)	topA	1156277..1158364 (-)	2088	WP_000179682.1	type I DNA topoisomerase	-
SPNOXC_RS06100 (SPNOXC11300)	-	1158531..1159574 (-)	1044	WP_001812883.1	TIGR00341 family protein	-
SPNOXC_RS13310	-	1160151..1160273 (+)	123	WP_001814242.1	hypothetical protein	-
SPNOXC_RS06105 (SPNOXC11310)	dprA/cilB/dalA	1160456..1161304 (-)	849	WP_000705300.1	DNA-processing protein DprA	Machinery gene
SPNOXC_RS06110 (SPNOXC11320)	-	1161390..1162079 (-)	690	WP_000643970.1	sugar phosphate nucleotidyltransferase	-
SPNOXC_RS06115 (SPNOXC11330)	-	1162091..1162969 (-)	879	WP_000837618.1	DMT family transporter	-
SPNOXC_RS06120 (SPNOXC11340)	licA	1162959..1163828 (-)	870	WP_000411215.1	choline kinase LicA	-
SPNOXC_RS06125 (SPNOXC11350)	-	1163845..1164867 (-)	1023	WP_000609890.1	ribitol-5-phosphate dehydrogenase	-
SPNOXC_RS06130 (SPNOXC11360)	-	1164872..1165579 (-)	708	WP_000638502.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31048.70 Da
• Isoelectric Point: 5.4047

>NTDB_id=49240 SPNOXC_RS06105 WP_000705300.1 1160456..1161304(-) (dprA/cilB/dalA) [Streptococcus pneumoniae OXC141]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDIFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=49240 SPNOXC_RS06105 WP_000705300.1 1160456..1161304(-) (dprA/cilB/dalA) [Streptococcus pneumoniae OXC141]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATCTCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAACAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGCTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACCTGTGAGCGAGCAATGGAAGAA
GGACGCGATATCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.291	100	0.993
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	97.872	100	0.979
dprA/cilB/dalA	Streptococcus mitis SK321	97.163	100	0.972
dprA	Streptococcus mutans UA159	62.857	99.291	0.624
dprA	Lactococcus lactis subsp. cremoris KW2	55.714	99.291	0.553
dprA	Staphylococcus aureus N315	37.102	100	0.372