Detailed information NTG0048883

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SGGB_RS00295
• Genome accession: NC_017576
• Coordinates: 48053..48952 (+)
• Length: 299 a.a.
• NCBI ID: WP_009853198.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus subsp. gallolyticus ATCC 43143
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 43053..53952

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGGB_RS00270 (SGGB_0032)	-	43252..43701 (+)	450	WP_012961319.1	DUF523 domain-containing protein	-
SGGB_RS00275 (SGGB_0033)	purE	43701..44189 (+)	489	WP_009853194.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
SGGB_RS00280 (SGGB_0034)	purK	44176..45249 (+)	1074	WP_009853195.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
SGGB_RS00285 (SGGB_0035)	-	45260..46306 (+)	1047	WP_014619874.1	hypothetical protein	-
SGGB_RS00290 (SGGB_0036)	purB	46608..47906 (+)	1299	WP_009853197.1	adenylosuccinate lyase	-
SGGB_RS00295 (SGGB_0037)	comR	48053..48952 (+)	900	WP_009853198.1	helix-turn-helix domain-containing protein	Regulator
SGGB_RS00305 (SGGB_0038)	-	50194..50625 (+)	432	WP_012961321.1	low molecular weight protein-tyrosine-phosphatase	-
SGGB_RS00310 (SGGB_0039)	-	50645..51025 (+)	381	WP_009853201.1	membrane protein	-
SGGB_RS00315 (SGGB_0040)	-	51022..52815 (+)	1794	WP_012961323.1	acyltransferase family protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 34967.15 Da
• Isoelectric Point: 5.1732

>NTDB_id=48883 SGGB_RS00295 WP_009853198.1 48053..48952(+) (comR) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MEKFGIKVRALREKKGISREEFCGDETELSVRQLARIEKGQSVPTLNKVGYIAKVLGVTIGELTDGKNLELPTRYKELKY
LLLRTPTYGDKERLKRQTSYFDEISEKYYEVIPEEERLIIDCLQSKIDVHFSDDVNFGEGILNDYFDQVRRKKNFQINDL
ILIDLYFACLASAKSFVGIYSLDLYDELMECLLNQENLSPETSLILNNVLLNNVDLVLRFHRESFMKRIIIKSDTIMTSV
HDFQRRPVLSLVEWKYYLQFKKDFLAAQKSYSNAILFANLIGDTYLENKLIEEWNNDTT

Nucleotide

• Length: 900 bp

>NTDB_id=48883 SGGB_RS00295 WP_009853198.1 48053..48952(+) (comR) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
TTGGAAAAGTTTGGGATTAAAGTACGTGCATTAAGAGAGAAAAAAGGGATTTCACGTGAAGAATTCTGTGGTGATGAAAC
AGAATTATCTGTGAGACAGCTAGCTAGAATTGAAAAAGGACAATCCGTCCCAACTCTTAATAAGGTGGGATATATTGCAA
AAGTATTAGGAGTAACTATTGGTGAGTTAACTGATGGTAAAAATTTAGAACTTCCCACTCGGTATAAGGAGTTAAAATAT
TTACTATTACGAACACCAACTTATGGGGATAAGGAACGTCTTAAGAGACAAACTTCATATTTTGATGAAATTTCAGAAAA
ATACTATGAAGTTATACCTGAAGAAGAACGCTTAATTATTGATTGTTTACAATCGAAGATTGATGTTCATTTTAGTGATG
ATGTTAATTTTGGTGAAGGAATTTTAAATGATTATTTTGACCAAGTTAGACGAAAGAAGAACTTTCAAATTAATGATTTG
ATTTTAATAGATTTATATTTTGCTTGCCTTGCTTCTGCTAAATCGTTTGTGGGAATCTATAGCTTAGATTTGTATGATGA
ATTAATGGAGTGTTTACTAAATCAAGAAAATCTTTCACCAGAAACTTCTTTGATTTTAAATAATGTTTTGTTAAATAATG
TAGATTTGGTTTTACGATTCCATAGAGAATCTTTTATGAAACGAATTATTATAAAAAGTGACACTATCATGACAAGTGTT
CATGATTTTCAAAGACGTCCAGTTTTAAGTTTAGTTGAGTGGAAATATTATTTACAATTTAAAAAAGATTTTTTAGCGGC
ACAAAAATCTTACTCCAATGCTATTTTATTTGCTAACTTAATTGGAGATACTTATTTGGAAAATAAGTTAATAGAAGAAT
GGAATAATGACACAACATGA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (8-63)

• ComR tetratricopeptide (ComR_TPR) (72-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	72.474	95.987	0.696
comR	Streptococcus mutans UA159	54.515	100	0.545
comR	Streptococcus pyogenes MGAS8232	49.333	100	0.495
comR	Streptococcus pyogenes MGAS315	47.315	99.666	0.472
comR	Streptococcus suis P1/7	39.799	100	0.398
comR	Streptococcus suis 05ZYH33	39.799	100	0.398
comR	Streptococcus suis D9	37.71	99.331	0.375