Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   IBL27_RS00355 Genome accession   NZ_CP061071
Coordinates   62977..63891 (+) Length   304 a.a.
NCBI ID   WP_002266376.1    Uniprot ID   -
Organism   Streptococcus mutans B04Sm5     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 57977..68891
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBL27_RS00335 (IBL27_00335) - 58270..59664 (+) 1395 WP_002310876.1 AAA family ATPase -
  IBL27_RS00340 (IBL27_00340) - 59624..60532 (+) 909 WP_002308398.1 DUF4435 domain-containing protein -
  IBL27_RS00345 (IBL27_00345) purB 60587..61885 (+) 1299 WP_002308396.1 adenylosuccinate lyase -
  IBL27_RS00350 (IBL27_00350) - 61905..62591 (+) 687 WP_002279174.1 DNA alkylation repair protein -
  IBL27_RS00355 (IBL27_00355) comR 62977..63891 (+) 915 WP_002266376.1 helix-turn-helix domain-containing protein Regulator
  IBL27_RS00360 (IBL27_00360) - 64425..66269 (-) 1845 WP_002288542.1 carbohydrate-binding domain-containing protein -
  IBL27_RS00365 (IBL27_00365) ruvB 66605..67600 (+) 996 WP_002269367.1 Holliday junction branch migration DNA helicase RuvB -
  IBL27_RS00370 (IBL27_00370) - 67638..68063 (+) 426 WP_002264681.1 low molecular weight protein-tyrosine-phosphatase -
  IBL27_RS00375 (IBL27_00375) - 68128..68511 (+) 384 WP_011074470.1 membrane protein -

Sequence

Protein


Download         Length: 304 a.a.        Molecular weight: 35246.44 Da        Isoelectric Point: 5.1281

>NTDB_id=480210 IBL27_RS00355 WP_002266376.1 62977..63891(+) (comR) [Streptococcus mutans B04Sm5]
MLKDFGKKIKSLRLEKGLTKEAVCLDESQLSTRQLTRIESGQSMPTLNKAIYIAGRLGVTLGYLTDGENVELPSRYKELK
YLLLRTPTYGDQQRLAEKETYFDEIFSQFYDDLPEEEQLIIDGLQSKLDIHFSDNIDFGVGILNDYFDQILRKTNYQVND
LILIDLYFSCLTVSGLDSAIFDSRKYNQLLETLLKQVDCLPLEDLFVLNNVLLNNFGLLLELKKYDFVKQLIAVSNKIMA
RTHDFQKKPIVNLLTWKHHLFVEKDYAKAKKSYDAAILFAQLTENINLRENLEKEWQKDSQNGT

Nucleotide


Download         Length: 915 bp        

>NTDB_id=480210 IBL27_RS00355 WP_002266376.1 62977..63891(+) (comR) [Streptococcus mutans B04Sm5]
ATGTTAAAAGATTTTGGGAAGAAAATTAAGAGCCTGAGGTTAGAAAAGGGGCTGACCAAAGAGGCTGTCTGCCTTGATGA
ATCGCAGTTGTCAACACGGCAGCTGACTAGAATTGAATCAGGACAGTCTATGCCAACTCTTAATAAAGCTATTTATATTG
CAGGACGTTTAGGAGTAACGCTTGGCTATTTAACGGACGGAGAAAATGTCGAGTTACCCAGTCGTTATAAAGAACTAAAA
TATTTATTATTACGAACGCCAACCTATGGTGACCAACAAAGATTAGCTGAAAAAGAAACCTATTTTGACGAGATTTTTAG
TCAGTTTTATGATGATTTGCCTGAAGAAGAACAATTGATTATTGATGGTTTACAATCGAAACTAGATATTCATTTTAGTG
ACAATATCGATTTTGGCGTTGGTATTTTAAATGACTATTTTGATCAGATTTTAAGAAAAACCAATTATCAGGTCAATGAT
TTGATTCTGATTGATCTCTATTTTTCCTGCTTAACTGTTAGTGGTTTGGATTCAGCTATTTTTGATTCAAGAAAATATAA
TCAATTATTGGAGACATTGCTTAAGCAGGTAGACTGCCTTCCATTGGAAGATCTTTTCGTTTTAAATAATGTTTTATTGA
ATAATTTTGGACTCCTCTTAGAATTGAAAAAATATGATTTTGTTAAGCAGCTTATTGCTGTTAGCAATAAAATCATGGCT
AGAACTCATGATTTTCAAAAAAAGCCTATTGTTAATCTTCTGACATGGAAGCATCATTTATTTGTTGAAAAAGATTATGC
GAAAGCTAAAAAGAGCTATGATGCTGCTATCTTATTTGCCCAGTTAACAGAAAACATTAATTTAAGAGAAAATTTGGAGA
AAGAATGGCAAAAAGATTCTCAGAACGGGACATAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(9-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

98.684

100

0.987
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

52.778

94.737

0.5
  comR Streptococcus pyogenes MGAS8232

47.351

99.342

0.47
  comR Streptococcus pyogenes MGAS315

47.492

98.355

0.467
  comR Streptococcus suis P1/7

43.478

98.355

0.428
  comR Streptococcus suis 05ZYH33

43.478

98.355

0.428
  comR Streptococcus suis D9

37

98.684

0.365