Detailed information NTG0479745

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: IBB94_RS01505
• Genome accession: NZ_CP061024
• Coordinates: 277108..278007 (+)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus strain 13498
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 272108..283007

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBB94_RS01485 (IBB94_01485)	trkA	273244..274593 (-)	1350	WP_207559738.1	Trk system potassium transporter TrkA	-
IBB94_RS01490 (IBB94_01490)	-	274882..275391 (+)	510	WP_014607952.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
IBB94_RS01495 (IBB94_01495)	-	275703..276260 (+)	558	WP_002949523.1	ECF transporter S component	-
IBB94_RS01500 (IBB94_01500)	-	276263..276913 (+)	651	WP_011225447.1	phosphatase PAP2 family protein	-
IBB94_RS01505 (IBB94_01505)	comR	277108..278007 (+)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
IBB94_RS10325 (IBB94_01510)	-	278182..280277 (+)	2096	Protein_249	peptide cleavage/export ABC transporter	-
IBB94_RS01515 (IBB94_01515)	-	280385..280702 (+)	318	WP_179970762.1	DUF805 domain-containing protein	-
IBB94_RS10330	-	280918..281265 (-)	348	WP_232085744.1	DUF4153 domain-containing protein	-
IBB94_RS09735	-	281190..281810 (-)	621	WP_232085704.1	DUF4153 domain-containing protein	-
IBB94_RS01525 (IBB94_01525)	-	282491..283006 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=479745 IBB94_RS01505 WP_014607953.1 277108..278007(+) (comR) [Streptococcus thermophilus strain 13498]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=479745 IBB94_RS01505 WP_014607953.1 277108..278007(+) (comR) [Streptococcus thermophilus strain 13498]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418