Detailed information NTG0047892

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NMBG2136_RS00625
• Genome accession: NC_017513
• Coordinates: 117238..118425 (+)
• Length: 395 a.a.
• NCBI ID: WP_002233405.1
• Uniprot ID: -
• Organism: Neisseria meningitidis G2136
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 112238..123425

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMBG2136_RS00610 (NMBG2136_0107)	-	113161..113760 (+)	600	WP_002216221.1	DUF4390 domain-containing protein	-
NMBG2136_RS00615 (NMBG2136_0108)	-	113760..115877 (+)	2118	WP_002230186.1	sensor histidine kinase	-
NMBG2136_RS00620 (NMBG2136_0109)	-	115870..117147 (+)	1278	WP_002233404.1	sigma-54-dependent transcriptional regulator	-
NMBG2136_RS00625 (NMBG2136_0110)	dprA	117238..118425 (+)	1188	WP_002233405.1	DNA-processing protein DprA	Machinery gene
NMBG2136_RS00630 (NMBG2136_0111)	-	118451..118912 (+)	462	WP_002215351.1	DUF494 domain-containing protein	-
NMBG2136_RS00635 (NMBG2136_0112)	topA	118984..121290 (+)	2307	WP_002238601.1	type I DNA topoisomerase	-
NMBG2136_RS00640 (NMBG2136_0113)	-	121363..122058 (-)	696	WP_002216227.1	hypothetical protein	-
NMBG2136_RS00650 (NMBG2136_0115)	-	122749..123126 (+)	378	WP_002233408.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 41956.04 Da
• Isoelectric Point: 6.1732

>NTDB_id=47892 NMBG2136_RS00625 WP_002233405.1 117238..118425(+) (dprA) [Neisseria meningitidis G2136]
MTEDERFAWLQLAFTPYIGAESFLLLMRRFGSAQNALSAPAEQVAPAVRHKQAAEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGKSLGGQNIPVVSGMASGIDT
AAHQGALEAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLVECLDDILNECPGLLQNTGASSYSINKDTPDTGRRAVQT
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=47892 NMBG2136_RS00625 WP_002233405.1 117238..118425(+) (dprA) [Neisseria meningitidis G2136]
ATGACAGAGGACGAACGTTTCGCGTGGTTGCAACTGGCTTTTACGCCCTATATCGGTGCGGAAAGTTTCTTGCTGCTGAT
GCGCCGTTTCGGCAGCGCGCAAAATGCCTTGTCCGCACCGGCGGAACAGGTCGCCCCGGCGGTGCGGCACAAGCAGGCGG
CCGAGGCTTGGCGCAATGCGGAAAAACGCGCTTTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAAGTCGTTGGGCGGGCAAAATATCCCCGTTGTGTCGGGTATGGCTTCCGGTATCGATACT
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGTATAGACCGCATTTACCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGATTGATTGTCAGCGAGTTTCCCATCGGTACGCGCCCGTATG
CCGGCAATTTTCCGCGCCGCAACCGCCTGATTGCTGCCCTGTCGCAAGTAACGCTGGTGGTTGAAGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGCTTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAATCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCAAAATTGGTGGAATGCCTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCATCATATTCTATAAATAAGGATACGCCCGACACGGGCCGCCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (79-283)

• DprA winged helix domain (DprA_WH) (341-388)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae MS11	97.215	100	0.972
dprA	Neisseria gonorrhoeae strain FA1090	96.962	100	0.97
dprA	Neisseria meningitidis strain C311	90.932	100	0.914
dprA	Neisseria meningitidis MC58	90.932	100	0.914
dprA	Vibrio cholerae strain A1552	37.783	100	0.38
dprA	Glaesserella parasuis strain SC1401	42.56	85.063	0.362