Detailed information NTG0047884

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NMAA_RS11250
• Genome accession: NC_017512
• Coordinates: 2135729..2136916 (-)
• Length: 395 a.a.
• NCBI ID: WP_002245787.1
• Uniprot ID: -
• Organism: Neisseria meningitidis WUE 2594
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2130729..2141916

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMAA_RS11225 (NMAA_1860)	-	2131026..2131406 (-)	381	WP_002239423.1	helix-turn-helix domain-containing protein	-
NMAA_RS11230 (NMAA_1861)	-	2131525..2132076 (+)	552	WP_002230190.1	hypothetical protein	-
NMAA_RS11235 (NMAA_1862)	-	2132096..2132791 (+)	696	WP_002245789.1	hypothetical protein	-
NMAA_RS11240 (NMAA_1863)	topA	2132864..2135170 (-)	2307	WP_002245788.1	type I DNA topoisomerase	-
NMAA_RS11245 (NMAA_1864)	-	2135242..2135703 (-)	462	WP_002215351.1	DUF494 domain-containing protein	-
NMAA_RS11250 (NMAA_1865)	dprA	2135729..2136916 (-)	1188	WP_002245787.1	DNA-processing protein DprA	Machinery gene
NMAA_RS11255 (NMAA_1866)	-	2137007..2138284 (-)	1278	WP_002245786.1	sigma-54-dependent transcriptional regulator	-
NMAA_RS11260 (NMAA_1867)	-	2138277..2140397 (-)	2121	WP_002245785.1	sensor histidine kinase	-
NMAA_RS11265 (NMAA_1868)	-	2140397..2140996 (-)	600	WP_002216221.1	DUF4390 domain-containing protein	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 42042.22 Da
• Isoelectric Point: 6.1732

>NTDB_id=47884 NMAA_RS11250 WP_002245787.1 2135729..2136916(-) (dprA) [Neisseria meningitidis WUE 2594]
MTEDERFAWLQLAFTPYIGAESFLLLMRRFGSAQNALSAPAEQVAALIRHKQALEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGKSLGGQNIPVVSGMASGIDT
AAHQGALEAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLVECLDDILNECPGLLQNTGASSYSINKDTPDTGRRAVQT
AYAPPPAAKMPSEAAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=47884 NMAA_RS11250 WP_002245787.1 2135729..2136916(-) (dprA) [Neisseria meningitidis WUE 2594]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGTTTCCTGCTGCTGAT
GCGCCGTTTCGGCAGCGCGCAAAATGCCCTGTCCGCACCGGCGGAACAGGTGGCGGCACTGATACGGCACAAACAGGCGC
TTGAGGCTTGGCGCAATGCGGAAAAACGCGCTCTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAAGTCGTTGGGCGGGCAAAATATCCCCGTTGTGTCGGGTATGGCTTCCGGTATCGATACT
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGTATAGACCGCATTTACCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGATTGATTGTCAGCGAGTTTCCCATCGGTACGCGCCCGTATG
CCGGCAATTTTCCGCGCCGCAACCGCCTGATTGCCGCCCTGTCGCAAGTAACGCTGGTGGTTGAAGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGCCTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAATCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCAAAATTGGTGGAATGCCTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCATCATATTCTATAAATAAGGATACGCCCGACACGGGACGCCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGCGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (339-388)

• DNA recombination-mediator protein A (DNA_processg_A) (79-283)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae MS11	96.456	100	0.965
dprA	Neisseria gonorrhoeae strain FA1090	96.203	100	0.962
dprA	Neisseria meningitidis strain C311	91.94	100	0.924
dprA	Neisseria meningitidis MC58	91.94	100	0.924
dprA	Vibrio cholerae strain A1552	37.783	100	0.38
dprA	Glaesserella parasuis strain SC1401	41.935	86.329	0.362