Detailed information NTG0477531

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7786_RS04865
• Genome accession: NZ_CP060649
• Coordinates: 962799..963635 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY270
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 957799..968635

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7786_RS04835 (H7786_04900)	-	958350..958721 (+)	372	WP_014407581.1	hypothetical protein	-
H7786_RS04840 (H7786_04905)	-	958771..959682 (-)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
H7786_RS04845 (H7786_04910)	trhA	959799..960449 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
H7786_RS04850 (H7786_04915)	-	960446..960886 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
H7786_RS04855 (H7786_04920)	ylqF	961105..961953 (+)	849	WP_030125932.1	ribosome biogenesis GTPase YlqF	-
H7786_RS04860 (H7786_04925)	-	961943..962734 (+)	792	WP_030125931.1	ribonuclease HII	-
H7786_RS04865 (H7786_04930)	dprA	962799..963635 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
H7786_RS04870 (H7786_04935)	topA	963742..965871 (+)	2130	WP_030125930.1	type I DNA topoisomerase	-
H7786_RS04875 (H7786_04940)	-	965946..966803 (-)	858	Protein_927	LysR family transcriptional regulator	-
H7786_RS04880 (H7786_04945)	-	966843..967409 (+)	567	Protein_928	PTS sugar transporter subunit IIC	-
H7786_RS04885 (H7786_04950)	-	967424..968416 (+)	993	WP_002989762.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=477531 H7786_RS04865 WP_002989770.1 962799..963635(+) (dprA) [Streptococcus pyogenes strain TSPY270]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=477531 H7786_RS04865 WP_002989770.1 962799..963635(+) (dprA) [Streptococcus pyogenes strain TSPY270]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367