Detailed information NTG0477466

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7787_RS04320
• Genome accession: NZ_CP060648
• Coordinates: 870015..870851 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY383
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 865015..875851

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7787_RS04290 (H7787_04285)	-	865569..865937 (+)	369	WP_010922310.1	hypothetical protein	-
H7787_RS04295 (H7787_04290)	-	865987..866898 (-)	912	WP_010922311.1	diacylglycerol/lipid kinase family protein	-
H7787_RS04300 (H7787_04295)	trhA	867015..867665 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
H7787_RS04305 (H7787_04300)	-	867662..868102 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
H7787_RS04310 (H7787_04305)	ylqF	868321..869169 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
H7787_RS04315 (H7787_04310)	-	869159..869950 (+)	792	WP_011285534.1	ribonuclease HII	-
H7787_RS04320 (H7787_04315)	dprA	870015..870851 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
H7787_RS04325 (H7787_04320)	topA	870958..873087 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
H7787_RS04330 (H7787_04325)	-	873162..874044 (-)	883	Protein_832	LysR family transcriptional regulator	-
H7787_RS04335 (H7787_04330)	-	874057..874602 (+)	546	Protein_833	PTS sugar transporter subunit IIC	-
H7787_RS04340 (H7787_04335)	-	874617..875609 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=477466 H7787_RS04320 WP_010922314.1 870015..870851(+) (dprA) [Streptococcus pyogenes strain TSPY383]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=477466 H7787_RS04320 WP_010922314.1 870015..870851(+) (dprA) [Streptococcus pyogenes strain TSPY383]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367