Detailed information NTG0477419

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7788_RS04610
• Genome accession: NZ_CP060647
• Coordinates: 903295..904131 (+)
• Length: 278 a.a.
• NCBI ID: WP_030127252.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY136
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 898295..909131

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7788_RS04580 (H7788_04580)	-	898783..899217 (+)	435	WP_011017767.1	hypothetical protein	-
H7788_RS04585 (H7788_04585)	-	899267..900178 (-)	912	WP_011184516.1	diacylglycerol/lipid kinase family protein	-
H7788_RS04590 (H7788_04590)	trhA	900295..900945 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
H7788_RS04595 (H7788_04595)	-	900942..901382 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
H7788_RS04600 (H7788_04600)	ylqF	901601..902449 (+)	849	WP_228614900.1	ribosome biogenesis GTPase YlqF	-
H7788_RS04605 (H7788_04605)	-	902439..903230 (+)	792	WP_030127253.1	ribonuclease HII	-
H7788_RS04610 (H7788_04610)	dprA	903295..904131 (+)	837	WP_030127252.1	DNA-processing protein DprA	Machinery gene
H7788_RS04615 (H7788_04615)	topA	904238..906367 (+)	2130	WP_030127251.1	type I DNA topoisomerase	-
H7788_RS04620 (H7788_04620)	trmFO	906502..907848 (+)	1347	WP_030127250.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31087.09 Da
• Isoelectric Point: 9.2565

>NTDB_id=477419 H7788_RS04610 WP_030127252.1 903295..904131(+) (dprA) [Streptococcus pyogenes strain TSPY136]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSNTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=477419 H7788_RS04610 WP_030127252.1 903295..904131(+) (dprA) [Streptococcus pyogenes strain TSPY136]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCAATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367