Detailed information NTG0477313

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7790_RS04755
• Genome accession: NZ_CP060645
• Coordinates: 943407..944243 (+)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY1349
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 938407..949243

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7790_RS04725 (H7790_04755)	-	938958..939329 (+)	372	WP_032463865.1	hypothetical protein	-
H7790_RS04730 (H7790_04760)	-	939379..940290 (-)	912	WP_002984631.1	diacylglycerol/lipid kinase family protein	-
H7790_RS04735 (H7790_04765)	trhA	940407..941057 (-)	651	WP_115230523.1	PAQR family membrane homeostasis protein TrhA	-
H7790_RS04740 (H7790_04770)	-	941054..941494 (-)	441	WP_002984627.1	DUF1836 domain-containing protein	-
H7790_RS04745 (H7790_04775)	ylqF	941713..942561 (+)	849	WP_002995004.1	ribosome biogenesis GTPase YlqF	-
H7790_RS04750 (H7790_04780)	-	942551..943342 (+)	792	WP_002995007.1	ribonuclease HII	-
H7790_RS04755 (H7790_04785)	dprA	943407..944243 (+)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
H7790_RS04760 (H7790_04790)	topA	944359..946488 (+)	2130	WP_115230522.1	type I DNA topoisomerase	-
H7790_RS04765 (H7790_04795)	-	946563..947420 (-)	858	Protein_917	LysR family transcriptional regulator	-
H7790_RS04770 (H7790_04800)	-	947460..948026 (+)	567	Protein_918	PTS sugar transporter subunit IIC	-
H7790_RS04775 (H7790_04805)	-	948041..949033 (+)	993	WP_115230520.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=477313 H7790_RS04755 WP_002995009.1 943407..944243(+) (dprA) [Streptococcus pyogenes strain TSPY1349]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=477313 H7790_RS04755 WP_002995009.1 943407..944243(+) (dprA) [Streptococcus pyogenes strain TSPY1349]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367