Detailed information NTG0047725

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NMV_RS00630
• Genome accession: NC_017501
• Coordinates: 123270..124457 (+)
• Length: 395 a.a.
• NCBI ID: WP_014573704.1
• Uniprot ID: A0A9K2KLV9
• Organism: Neisseria meningitidis 8013
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 118270..129457

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMV_RS00615 (NMV_0124)	-	119190..119789 (+)	600	WP_002216221.1	DUF4390 domain-containing protein	-
NMV_RS00620 (NMV_0125)	-	119789..121909 (+)	2121	WP_014573703.1	sensor histidine kinase	-
NMV_RS00625 (NMV_0126)	-	121902..123179 (+)	1278	WP_002234456.1	sigma-54-dependent transcriptional regulator	-
NMV_RS00630 (NMV_0127)	dprA	123270..124457 (+)	1188	WP_014573704.1	DNA-processing protein DprA	Machinery gene
NMV_RS00635 (NMV_0128)	-	124483..124944 (+)	462	WP_002215351.1	DUF494 domain-containing protein	-
NMV_RS00640 (NMV_0129)	topA	125016..127322 (+)	2307	WP_014573705.1	type I DNA topoisomerase	-
NMV_RS00645 (NMV_0130)	-	127395..128090 (-)	696	WP_002245789.1	hypothetical protein	-
NMV_RS00650 (NMV_0131)	-	128110..128661 (-)	552	WP_002215355.1	hypothetical protein	-
NMV_RS00655 (NMV_0132)	-	128780..129157 (+)	378	WP_002233408.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 41974.14 Da
• Isoelectric Point: 6.1732

>NTDB_id=47725 NMV_RS00630 WP_014573704.1 123270..124457(+) (dprA) [Neisseria meningitidis 8013]
MTEDERFAWLQLAFTPYIGAESFLLLMRRFGSAQNALSAPAEQVAALIRHKQALEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRTLSGKGIPVVSGMASGIDT
AAHQGALEAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLVECLDDILNECPGLLQNTGASSYSINKDTPDTGSRAVQT
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=47725 NMV_RS00630 WP_014573704.1 123270..124457(+) (dprA) [Neisseria meningitidis 8013]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGTTTCCTGCTGCTGAT
GCGCCGTTTCGGCAGCGCGCAAAATGCCCTGTCCGCACCGGCGGAACAGGTGGCGGCACTGATACGGCACAAACAGGCGC
TTGAGGCTTGGCGCAATGCGGAAAAACGCGCTCTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGTAGGACGTTGTCTGGGAAAGGCATTCCCGTTGTGTCGGGTATGGCTTCGGGCATCGATACC
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCATCGCTGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGGCTGATTGTCAGCGAGTTCCCCATCGGTACGCGGCCGTATG
CCGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTTGAAGCTGCGTTGGAATCC
GGTTCGCTGATTACCGCCGGCTTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAATCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAATTGGTGGAATGCCTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCATCATATTCTATAAATAAGGATACGCCCGACACGGGCAGTCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (341-388)

• DNA recombination-mediator protein A (DNA_processg_A) (79-283)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae MS11	96.962	100	0.97
dprA	Neisseria gonorrhoeae strain FA1090	96.709	100	0.967
dprA	Neisseria meningitidis MC58	91.688	100	0.922
dprA	Neisseria meningitidis strain C311	91.688	100	0.922
dprA	Vibrio cholerae strain A1552	37.783	100	0.38
dprA	Vibrio campbellii strain DS40M4	36.856	98.228	0.362
dprA	Glaesserella parasuis strain SC1401	42.059	86.076	0.362