Detailed information NTG0477205

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7792_RS04190
• Genome accession: NZ_CP060643
• Coordinates: 850940..851776 (-)
• Length: 278 a.a.
• NCBI ID: WP_228650393.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY416
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 845940..856776

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7792_RS04170 (H7792_04160)	-	846158..847150 (-)	993	WP_228650392.1	D-lactate dehydrogenase	-
H7792_RS04175 (H7792_04165)	-	847165..847731 (-)	567	Protein_769	PTS sugar transporter subunit IIC	-
H7792_RS04180 (H7792_04170)	-	847771..848628 (+)	858	Protein_770	LysR family transcriptional regulator	-
H7792_RS04185 (H7792_04175)	topA	848703..850832 (-)	2130	WP_111713773.1	type I DNA topoisomerase	-
H7792_RS04190 (H7792_04180)	dprA	850940..851776 (-)	837	WP_228650393.1	DNA-processing protein DprA	Machinery gene
H7792_RS04195 (H7792_04185)	-	851841..852632 (-)	792	WP_109991958.1	ribonuclease HII	-
H7792_RS04200 (H7792_04190)	ylqF	852622..853470 (-)	849	WP_111713774.1	ribosome biogenesis GTPase YlqF	-
H7792_RS04205 (H7792_04195)	-	853689..854129 (+)	441	WP_111713775.1	DUF1836 domain-containing protein	-
H7792_RS04210 (H7792_04200)	trhA	854126..854776 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
H7792_RS04215 (H7792_04205)	-	854893..855804 (+)	912	WP_047235287.1	diacylglycerol/lipid kinase family protein	-
H7792_RS04220 (H7792_04210)	-	855854..856222 (-)	369	WP_010922310.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31149.07 Da
• Isoelectric Point: 8.3304

>NTDB_id=477205 H7792_RS04190 WP_228650393.1 850940..851776(-) (dprA) [Streptococcus pyogenes strain TSPY416]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYSPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEDR
DIFAVPGNILDEKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=477205 H7792_RS04190 WP_228650393.1 850940..851776(-) (dprA) [Streptococcus pyogenes strain TSPY416]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACAGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGACCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGAGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae D39	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae R6	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis SK321	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.353	100	0.594
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367