Detailed information NTG0477153

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7793_RS04935
• Genome accession: NZ_CP060642
• Coordinates: 962568..963404 (-)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY1312
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 957568..968404

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7793_RS04915 (H7793_04915)	-	957787..958779 (-)	993	WP_002989762.1	D-lactate dehydrogenase	-
H7793_RS04920 (H7793_04920)	-	958794..959360 (-)	567	Protein_920	PTS sugar transporter subunit IIC	-
H7793_RS04925 (H7793_04925)	-	959400..960257 (+)	858	Protein_921	LysR family transcriptional regulator	-
H7793_RS04930 (H7793_04930)	topA	960332..962461 (-)	2130	WP_002989768.1	type I DNA topoisomerase	-
H7793_RS04935 (H7793_04935)	dprA	962568..963404 (-)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
H7793_RS04940 (H7793_04940)	-	963469..964260 (-)	792	WP_002989771.1	ribonuclease HII	-
H7793_RS04945 (H7793_04945)	ylqF	964250..965098 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
H7793_RS04950 (H7793_04950)	-	965317..965757 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
H7793_RS04955 (H7793_04955)	trhA	965754..966404 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
H7793_RS04960 (H7793_04960)	-	966521..967432 (+)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
H7793_RS04965 (H7793_04965)	-	967482..967922 (-)	441	WP_024623381.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=477153 H7793_RS04935 WP_002989770.1 962568..963404(-) (dprA) [Streptococcus pyogenes strain TSPY1312]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=477153 H7793_RS04935 WP_002989770.1 962568..963404(-) (dprA) [Streptococcus pyogenes strain TSPY1312]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367