Detailed information NTG0477104

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7795_RS04725
• Genome accession: NZ_CP060641
• Coordinates: 926166..927002 (-)
• Length: 278 a.a.
• NCBI ID: WP_023079425.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY210
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 921166..932002

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7795_RS04705 (H7795_04700)	-	921411..922389 (-)	979	Protein_874	D-lactate dehydrogenase	-
H7795_RS04710 (H7795_04705)	-	922404..922957 (-)	554	Protein_875	PTS sugar transporter subunit IIC	-
H7795_RS04715 (H7795_04710)	-	922970..923854 (+)	885	Protein_876	LysR family transcriptional regulator	-
H7795_RS04720 (H7795_04715)	topA	923929..926058 (-)	2130	WP_011017773.1	type I DNA topoisomerase	-
H7795_RS04725 (H7795_04720)	dprA	926166..927002 (-)	837	WP_023079425.1	DNA-processing protein DprA	Machinery gene
H7795_RS04730 (H7795_04725)	-	927067..927858 (-)	792	WP_023610685.1	ribonuclease HII	-
H7795_RS04735 (H7795_04730)	ylqF	927848..928696 (-)	849	WP_023612970.1	ribosome biogenesis GTPase YlqF	-
H7795_RS04740 (H7795_04735)	-	928915..929355 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
H7795_RS04745 (H7795_04740)	trhA	929352..930002 (+)	651	WP_023079408.1	PAQR family membrane homeostasis protein TrhA	-
H7795_RS04750 (H7795_04745)	-	930119..931030 (+)	912	WP_023079407.1	diacylglycerol/lipid kinase family protein	-
H7795_RS04755 (H7795_04750)	-	931080..931448 (-)	369	WP_010922310.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31046.98 Da
• Isoelectric Point: 8.5827

>NTDB_id=477104 H7795_RS04725 WP_023079425.1 926166..927002(-) (dprA) [Streptococcus pyogenes strain TSPY210]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEDR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=477104 H7795_RS04725 WP_023079425.1 926166..927002(-) (dprA) [Streptococcus pyogenes strain TSPY210]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTCAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGACCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367