Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   LLH_RS11750 Genome accession   NC_017492
Coordinates   2257821..2258057 (-) Length   78 a.a.
NCBI ID   WP_014573335.1    Uniprot ID   -
Organism   Lactococcus cremoris subsp. cremoris A76     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2252555..2260656 2257821..2258057 within 0


Gene organization within MGE regions


Location: 2252555..2260656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLH_RS11720 (llh_12275) - 2254015..2254824 (-) 810 WP_011677177.1 metal ABC transporter permease -
  LLH_RS11725 (llh_12280) - 2254817..2255554 (-) 738 WP_011677178.1 metal ABC transporter ATP-binding protein -
  LLH_RS11730 (llh_12285) - 2255733..2256575 (-) 843 WP_011677179.1 metal ABC transporter solute-binding protein, Zn/Mn family -
  LLH_RS11735 (llh_12290) - 2256572..2257009 (-) 438 WP_011677180.1 zinc-dependent MarR family transcriptional regulator -
  LLH_RS11740 (llh_12295) comGG 2257089..2257388 (-) 300 WP_011677181.1 competence type IV pilus minor pilin ComGG Machinery gene
  LLH_RS11745 comGF 2257412..2257837 (-) 426 WP_014735174.1 competence type IV pilus minor pilin ComGF Machinery gene
  LLH_RS11750 (llh_12305) comGE 2257821..2258057 (-) 237 WP_014573335.1 competence type IV pilus minor pilin ComGE Machinery gene
  LLH_RS14595 (llh_12310) comGD 2258089..2258277 (-) 189 WP_014573336.1 hypothetical protein Machinery gene
  LLH_RS11760 (llh_12320) comGC 2258479..2258829 (-) 351 WP_050574401.1 competence type IV pilus major pilin ComGC Machinery gene
  LLH_RS11765 (llh_12325) comGB 2258874..2259899 (-) 1026 WP_050574400.1 competence type IV pilus assembly protein ComGB Machinery gene
  LLH_RS11770 (llh_12330) - 2259799..2260620 (-) 822 Protein_2274 ATPase, T2SS/T4P/T4SS family -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 8700.94 Da        Isoelectric Point: 4.3885

>NTDB_id=47710 LLH_RS11750 WP_014573335.1 2257821..2258057(-) (comGE) [Lactococcus cremoris subsp. cremoris A76]
MALLSFLVTFLLSALTNSRQQEVQENQQIESLNVAQMAIESQLMELSLNGSVIKIRQDSTATIISDHGKEILRLEAQN

Nucleotide


Download         Length: 237 bp        

>NTDB_id=47710 LLH_RS11750 WP_014573335.1 2257821..2258057(-) (comGE) [Lactococcus cremoris subsp. cremoris A76]
ATGGCATTATTGAGCTTTTTGGTCACTTTTCTCTTAAGTGCTCTTACTAATTCTCGTCAGCAAGAGGTACAAGAAAATCA
ACAAATTGAGTCCTTAAATGTAGCTCAGATGGCAATAGAAAGTCAGCTGATGGAACTATCGTTAAATGGTTCTGTTATAA
AAATAAGACAAGATTCGACTGCAACCATTATTAGTGACCATGGAAAGGAAATTTTGCGACTTGAAGCTCAAAATTAG

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(1-74)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

96.154

100

0.962

Multiple sequence alignment