Detailed information NTG0476989

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7797_RS05110
• Genome accession: NZ_CP060639
• Coordinates: 1010957..1011793 (+)
• Length: 278 a.a.
• NCBI ID: WP_111693218.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY153
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1005957..1016793

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7797_RS05080 (H7797_05055)	-	1006512..1006880 (+)	369	WP_002994996.1	hypothetical protein	-
H7797_RS05085 (H7797_05060)	-	1006930..1007841 (-)	912	WP_047235287.1	diacylglycerol/lipid kinase family protein	-
H7797_RS05090 (H7797_05065)	trhA	1007958..1008608 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
H7797_RS05095 (H7797_05070)	-	1008605..1009045 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
H7797_RS05100 (H7797_05075)	ylqF	1009264..1010112 (+)	849	WP_038433405.1	ribosome biogenesis GTPase YlqF	-
H7797_RS05105 (H7797_05080)	-	1010102..1010893 (+)	792	WP_111693217.1	ribonuclease HII	-
H7797_RS05110 (H7797_05085)	dprA	1010957..1011793 (+)	837	WP_111693218.1	DNA-processing protein DprA	Machinery gene
H7797_RS05115 (H7797_05090)	topA	1011899..1014028 (+)	2130	WP_111693219.1	type I DNA topoisomerase	-
H7797_RS05120 (H7797_05095)	-	1014103..1014909 (-)	807	Protein_976	LysR family transcriptional regulator	-
H7797_RS05125 (H7797_05100)	-	1014922..1015479 (+)	558	Protein_977	PTS sugar transporter subunit IIC	-
H7797_RS05130 (H7797_05105)	-	1015494..1016486 (+)	993	WP_021340798.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31073.07 Da
• Isoelectric Point: 9.2565

>NTDB_id=476989 H7797_RS05110 WP_111693218.1 1010957..1011793(+) (dprA) [Streptococcus pyogenes strain TSPY153]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=476989 H7797_RS05110 WP_111693218.1 1010957..1011793(+) (dprA) [Streptococcus pyogenes strain TSPY153]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367