Detailed information NTG0476935

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7798_RS04370
• Genome accession: NZ_CP060638
• Coordinates: 885925..886761 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY141
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 880925..891761

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7798_RS04340 (H7798_04380)	-	881476..881847 (+)	372	WP_014407581.1	hypothetical protein	-
H7798_RS04345 (H7798_04385)	-	881897..882808 (-)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
H7798_RS04350 (H7798_04390)	trhA	882925..883575 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
H7798_RS04355 (H7798_04395)	-	883572..884012 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
H7798_RS04360 (H7798_04400)	ylqF	884231..885079 (+)	849	WP_030125932.1	ribosome biogenesis GTPase YlqF	-
H7798_RS04365 (H7798_04405)	-	885069..885860 (+)	792	WP_030125931.1	ribonuclease HII	-
H7798_RS04370 (H7798_04410)	dprA	885925..886761 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
H7798_RS04375 (H7798_04415)	topA	886868..888997 (+)	2130	WP_030125930.1	type I DNA topoisomerase	-
H7798_RS04380 (H7798_04420)	-	889072..889929 (-)	858	Protein_838	LysR family transcriptional regulator	-
H7798_RS04385 (H7798_04425)	-	889969..890535 (+)	567	Protein_839	PTS sugar transporter subunit IIC	-
H7798_RS04390 (H7798_04430)	-	890550..891541 (+)	992	Protein_840	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=476935 H7798_RS04370 WP_002989770.1 885925..886761(+) (dprA) [Streptococcus pyogenes strain TSPY141]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=476935 H7798_RS04370 WP_002989770.1 885925..886761(+) (dprA) [Streptococcus pyogenes strain TSPY141]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367