Detailed information NTG0474941

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H7X58_RS04705
• Genome accession: NZ_CP060268
• Coordinates: 933758..934594 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain SP1426
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 928758..939594

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7X58_RS04675 (H7X58_04660)	-	929312..929680 (+)	369	WP_010922310.1	hypothetical protein	-
H7X58_RS04680 (H7X58_04665)	-	929730..930641 (-)	912	WP_010922311.1	diacylglycerol/lipid kinase family protein	-
H7X58_RS04685 (H7X58_04670)	trhA	930758..931408 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
H7X58_RS04690 (H7X58_04675)	-	931405..931845 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
H7X58_RS04695 (H7X58_04680)	ylqF	932064..932912 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
H7X58_RS04700 (H7X58_04685)	-	932902..933693 (+)	792	WP_011285534.1	ribonuclease HII	-
H7X58_RS04705 (H7X58_04690)	dprA	933758..934594 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
H7X58_RS04710 (H7X58_04695)	topA	934701..936830 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
H7X58_RS04715 (H7X58_04700)	-	936905..937787 (-)	883	Protein_897	LysR family transcriptional regulator	-
H7X58_RS04720 (H7X58_04705)	-	937800..938345 (+)	546	Protein_898	PTS sugar transporter subunit IIC	-
H7X58_RS04725 (H7X58_04710)	-	938360..939352 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=474941 H7X58_RS04705 WP_010922314.1 933758..934594(+) (dprA) [Streptococcus pyogenes strain SP1426]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=474941 H7X58_RS04705 WP_010922314.1 933758..934594(+) (dprA) [Streptococcus pyogenes strain SP1426]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367