Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilQ   Type   Machinery gene
Locus tag   H3L95_RS08915 Genome accession   NZ_CP059566
Coordinates   1852105..1854240 (-) Length   711 a.a.
NCBI ID   WP_003759524.1    Uniprot ID   C6M757
Organism   Neisseria sicca strain DSM 17713     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1847105..1859240
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H3L95_RS08885 (H3L95_08885) mraZ 1847632..1848087 (-) 456 WP_003761336.1 division/cell wall cluster transcriptional repressor MraZ -
  H3L95_RS08890 (H3L95_08890) - 1848439..1849596 (+) 1158 WP_003761332.1 class I SAM-dependent methyltransferase -
  H3L95_RS08905 (H3L95_08905) aroB 1850201..1851280 (-) 1080 WP_003759527.1 3-dehydroquinate synthase -
  H3L95_RS08910 (H3L95_08910) - 1851366..1851878 (-) 513 WP_003765896.1 shikimate kinase -
  H3L95_RS08915 (H3L95_08915) pilQ 1852105..1854240 (-) 2136 WP_003759524.1 type IV pilus secretin PilQ Machinery gene
  H3L95_RS08920 (H3L95_08920) pilP 1854258..1854824 (-) 567 WP_003765902.1 pilus assembly protein PilP Machinery gene
  H3L95_RS08925 (H3L95_08925) - 1854842..1855534 (-) 693 WP_003759520.1 type 4a pilus biogenesis protein PilO -
  H3L95_RS08930 (H3L95_08930) pilN 1855535..1856152 (-) 618 WP_003759517.1 PilN domain-containing protein Machinery gene
  H3L95_RS08935 (H3L95_08935) pilM 1856154..1857263 (-) 1110 WP_003759516.1 type IV pilus assembly protein PilM -

Sequence

Protein


Download         Length: 711 a.a.        Molecular weight: 77803.10 Da        Isoelectric Point: 9.6387

>NTDB_id=470737 H3L95_RS08915 WP_003759524.1 1852105..1854240(-) (pilQ) [Neisseria sicca strain DSM 17713]
MKTKHMTKFFASIGVAMAVQTAFAGNITDINVSTLPDSQKIIKIRFDRDVTSPSGFVTSAPARIALDFANTTIRLPQSVL
EYADPLLNQITAAQNNDRSRIVLGLNKTAQYNTEIHGNEVWVFVSESADRNFAMSVSNNKPSMQDSVPSEKTKQVANSAN
IDFRKGSRNSGVVELSVPAFTGQPDIKQQRDRVIITLKNYPLPTQAQRSLDVGDFNTPVKNITLKRIGNDTQLIIRNSSN
WEVRTKPAAGHFTFEILPKAADTESRGLNGGNANKSFNGRKISLDFQDVEVRTILQILAKESGVNIVASDTVNGKMTLSL
KDVPWDQALDLVMQARNLDMRRQGNIINIAPRDELLAKDKAFLQAEKEIAELGPLYSQTFQLKYKNVEEFRKILRLEDNG
SSNSNGRNTLLSGRGSALIDPATNTLIVTDNRNVIEKFRKLIDELDVPTRQVMVEARIVEAKDGFSRDLGVKFGAAGARG
RNSWGNDWSAAQNNHNTNASVFRGESAYPTWSLQPNVSLPATAATNSIALVRALSSGALGLEISASEATGKSKTISNPRV
LTQDRREATIESGTEIPYQEASSSGATSVSFKKAVLGLTVTPNVTPDGQIIMTVKITKDTPVDCTVDSLITKCIQTKNLN
TQAMVEDGGTLIVGGIYEEDNSDTINKVPLLGDIPVVGNLFKSRAKKEERRELLIFITPRIMDGVGSNLRY

Nucleotide


Download         Length: 2136 bp        

>NTDB_id=470737 H3L95_RS08915 WP_003759524.1 1852105..1854240(-) (pilQ) [Neisseria sicca strain DSM 17713]
ATGAAAACTAAGCACATGACAAAATTTTTTGCCAGTATTGGCGTAGCCATGGCTGTGCAAACTGCTTTTGCAGGTAATAT
TACTGATATTAATGTATCTACTCTTCCTGATAGTCAAAAAATTATCAAAATCCGTTTTGATCGTGATGTAACCAGTCCGA
GCGGTTTTGTTACTTCGGCTCCAGCTAGAATTGCACTTGATTTTGCTAACACTACTATTCGATTGCCTCAATCAGTATTG
GAGTATGCCGATCCGTTATTAAATCAGATTACGGCGGCACAAAATAATGACCGTTCCCGTATTGTGTTGGGTTTGAATAA
AACTGCCCAATATAATACTGAAATTCATGGCAATGAAGTTTGGGTTTTTGTTAGCGAGTCAGCTGACCGAAATTTTGCAA
TGTCTGTATCAAATAATAAGCCTTCTATGCAGGATTCTGTTCCGTCAGAAAAAACAAAGCAAGTCGCTAATTCCGCTAAT
ATCGACTTCCGTAAAGGATCGCGCAATTCAGGTGTTGTTGAATTAAGCGTTCCGGCTTTTACTGGACAGCCTGATATTAA
ACAACAGCGTGATCGTGTCATCATTACATTGAAAAACTATCCGTTGCCAACACAAGCACAACGTAGTTTGGATGTAGGCG
ATTTCAATACACCTGTAAAAAATATAACTTTAAAACGAATCGGTAATGATACTCAGCTGATCATTCGAAATAGTTCAAAC
TGGGAAGTTCGTACTAAGCCGGCAGCAGGGCATTTTACTTTTGAAATTTTACCTAAAGCCGCTGATACGGAGTCACGTGG
TTTGAATGGTGGTAATGCAAATAAATCTTTCAATGGTCGTAAAATTTCTCTAGATTTCCAAGATGTTGAAGTTCGTACTA
TTTTGCAGATTCTTGCAAAAGAGTCCGGCGTCAATATTGTGGCTAGCGATACGGTAAATGGTAAGATGACTTTATCCCTC
AAGGATGTGCCTTGGGATCAGGCATTGGACTTGGTAATGCAAGCCCGTAATTTGGATATGCGTCGTCAAGGTAATATCAT
CAATATTGCTCCACGTGATGAATTGTTGGCGAAGGATAAGGCCTTCTTGCAAGCAGAAAAAGAAATTGCAGAGCTTGGTC
CTTTGTATTCACAAACCTTCCAATTGAAGTATAAAAATGTGGAGGAGTTCCGTAAAATCCTTCGTTTGGAAGACAACGGA
AGTAGCAATTCCAATGGTCGCAATACCTTGTTGAGCGGTCGAGGTAGTGCTTTGATTGACCCTGCAACAAATACCTTGAT
TGTTACGGATAATCGAAACGTCATCGAGAAATTCCGTAAATTGATTGATGAGTTGGATGTTCCTACACGCCAAGTTATGG
TTGAAGCGCGTATTGTAGAAGCAAAAGATGGATTCTCACGCGATTTGGGCGTTAAGTTTGGTGCTGCTGGTGCAAGAGGA
AGAAACTCTTGGGGCAATGATTGGTCAGCTGCTCAGAATAACCACAATACTAACGCCTCAGTGTTCCGCGGAGAGTCTGC
TTATCCAACTTGGTCTTTGCAGCCTAACGTAAGCTTACCTGCTACAGCAGCAACGAACAGTATCGCTTTAGTACGAGCCT
TGTCATCTGGTGCATTAGGTTTGGAAATCTCTGCGTCTGAAGCAACAGGTAAGAGCAAAACCATTTCTAATCCGCGTGTT
CTGACTCAGGATCGTCGAGAAGCTACGATTGAATCCGGTACCGAAATTCCTTACCAAGAAGCTTCTTCAAGCGGTGCGAC
TTCGGTTTCATTCAAAAAAGCGGTTTTGGGTCTGACAGTTACTCCTAATGTAACTCCGGATGGCCAAATTATTATGACCG
TTAAGATCACTAAAGATACTCCGGTCGACTGTACTGTAGATTCTTTGATAACCAAGTGTATTCAGACTAAGAACTTGAAT
ACTCAGGCTATGGTTGAAGATGGTGGCACTTTGATCGTTGGTGGTATCTATGAAGAGGACAATAGCGATACCATCAATAA
AGTTCCATTGCTTGGTGATATTCCTGTAGTAGGAAACTTGTTTAAATCACGAGCCAAGAAAGAAGAACGACGCGAATTGT
TGATTTTCATAACGCCTCGCATTATGGATGGCGTGGGTAGTAATTTGCGTTATTAA

Domains

Predicted by InterproScan.

AMIN domain (AMIN)

(40-122)

Secretin and TonB N terminus short domain (STN)

(304-351)

Bacterial type II/III secretion system short domain (Secretin_N)

(378-451)

Bacterial type II and III secretion system protein (Secretin)

(546-703)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C6M757

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilQ Neisseria gonorrhoeae strain FA1090

63.464

100

0.66
  pilQ Neisseria meningitidis MC58

69.604

78.2

0.544
  pilQ Neisseria meningitidis M1080

69.604

78.2

0.544