Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   H1R75_RS07355 Genome accession   NZ_CP059471
Coordinates   1452817..1453527 (-) Length   236 a.a.
NCBI ID   WP_182001280.1    Uniprot ID   -
Organism   Streptococcus equinus strain MDC1     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1447817..1458527
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1R75_RS07340 (H1R75_07340) rnc 1449765..1450451 (-) 687 WP_021142842.1 ribonuclease III -
  H1R75_RS07345 (H1R75_07345) vicX 1450662..1451471 (-) 810 WP_021142843.1 MBL fold metallo-hydrolase Regulator
  H1R75_RS07350 (H1R75_07350) vicK 1451472..1452824 (-) 1353 WP_027968495.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H1R75_RS07355 (H1R75_07355) vicR 1452817..1453527 (-) 711 WP_182001280.1 response regulator YycF Regulator
  H1R75_RS07360 (H1R75_07360) - 1453835..1454599 (+) 765 WP_024343734.1 amino acid ABC transporter ATP-binding protein -
  H1R75_RS07365 (H1R75_07365) - 1454610..1455413 (+) 804 WP_182001281.1 transporter substrate-binding domain-containing protein -
  H1R75_RS07370 (H1R75_07370) - 1455429..1456133 (+) 705 WP_039698014.1 amino acid ABC transporter permease -
  H1R75_RS07375 (H1R75_07375) - 1456143..1456790 (+) 648 WP_182001282.1 amino acid ABC transporter permease -
  H1R75_RS07380 (H1R75_07380) - 1456823..1457431 (-) 609 WP_074450680.1 TVP38/TMEM64 family protein -
  H1R75_RS07385 (H1R75_07385) - 1457649..1457945 (-) 297 WP_045797684.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27193.97 Da        Isoelectric Point: 4.6553

>NTDB_id=469843 H1R75_RS07355 WP_182001280.1 1452817..1453527(-) (vicR) [Streptococcus equinus strain MDC1]
MKKILIVDDEKPISDIIKFNLTKEGYETVTAFDGREAIEKFEEENPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASTSNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=469843 H1R75_RS07355 WP_182001280.1 1452817..1453527(-) (vicR) [Streptococcus equinus strain MDC1]
ATGAAAAAAATTCTTATTGTTGATGATGAAAAACCAATTTCAGATATTATTAAGTTTAATTTAACTAAAGAAGGTTACGA
AACAGTTACGGCTTTTGATGGTCGTGAAGCTATTGAAAAATTTGAAGAAGAAAATCCTGATTTGATTATTTTGGATTTGA
TGTTGCCAGAATTGGACGGACTTGAAGTCGCAAAAGAAGTTCGTAAAACAAGTCATATTCCTATTATTATGCTATCAGCA
AAAGATAGTGAATTTGATAAAGTTATCGGGCTTGAAATTGGTGCTGACGACTACGTGACAAAACCATTTTCAAACCGCGA
ATTGTTGGCTCGTGTCAAAGCACACCTTCGCCGCACTGAAAATATCGAATCTGCAGTTGCTGAAGAAAATGCGTCTACTT
CGAACTCAGAAATCACAATTGGTGACTTGAAAATCTTGCCTGATGCATTTGTGGCACAAAAACGTGGTGAAGACATTGAA
TTAACACACCGTGAGTTTGAATTGTTGCATCATTTGGCAACTCACATGGGACAAGTAATGACACGTGAATACCTTTTGGA
AACTGTTTGGGGTTATGACTATTTTGGTGATGTCCGTACGGTTGACGTAACAATCCGTCGTTTACGTGAAAAAATCGAAG
ACACACCAAGTCGTCCAGAATACATTTTGACACGTCGTGGTGTTGGATATTACATGAAGTCTTATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.678

100

0.907
  micA Streptococcus pneumoniae Cp1015

78.205

99.153

0.775
  covR Streptococcus salivarius strain HSISS4

47.414

98.305

0.466
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.121

98.305

0.453
  scnR Streptococcus mutans UA159

36.864

100

0.369