Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   H1R75_RS07350 Genome accession   NZ_CP059471
Coordinates   1451472..1452824 (-) Length   450 a.a.
NCBI ID   WP_027968495.1    Uniprot ID   -
Organism   Streptococcus equinus strain MDC1     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1446472..1457824
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1R75_RS07340 (H1R75_07340) rnc 1449765..1450451 (-) 687 WP_021142842.1 ribonuclease III -
  H1R75_RS07345 (H1R75_07345) vicX 1450662..1451471 (-) 810 WP_021142843.1 MBL fold metallo-hydrolase Regulator
  H1R75_RS07350 (H1R75_07350) vicK 1451472..1452824 (-) 1353 WP_027968495.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H1R75_RS07355 (H1R75_07355) vicR 1452817..1453527 (-) 711 WP_182001280.1 response regulator YycF Regulator
  H1R75_RS07360 (H1R75_07360) - 1453835..1454599 (+) 765 WP_024343734.1 amino acid ABC transporter ATP-binding protein -
  H1R75_RS07365 (H1R75_07365) - 1454610..1455413 (+) 804 WP_182001281.1 transporter substrate-binding domain-containing protein -
  H1R75_RS07370 (H1R75_07370) - 1455429..1456133 (+) 705 WP_039698014.1 amino acid ABC transporter permease -
  H1R75_RS07375 (H1R75_07375) - 1456143..1456790 (+) 648 WP_182001282.1 amino acid ABC transporter permease -
  H1R75_RS07380 (H1R75_07380) - 1456823..1457431 (-) 609 WP_074450680.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51377.32 Da        Isoelectric Point: 4.7300

>NTDB_id=469842 H1R75_RS07350 WP_027968495.1 1451472..1452824(-) (vicK) [Streptococcus equinus strain MDC1]
MNNIMSQNQYLFEQAILFLLAFVAVYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQQQLNLEREEALGMNIVDILGDDSDYSYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWLEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDDED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=469842 H1R75_RS07350 WP_027968495.1 1451472..1452824(-) (vicK) [Streptococcus equinus strain MDC1]
ATGAATAATATAATGTCACAGAATCAGTATCTGTTTGAGCAGGCAATCTTGTTTTTGCTCGCTTTTGTCGCTGTTTATTT
TATTCATTTAGCGATAAGAGATTATCGAACTTCAGTTAATATTCGTCGTTTGAGTGGTAAGGTTCGTGAGCTTATCACTG
GTAAATACACTGAAGACATCATTATTGAAAAAGATAGAGATTTGGCTGAACTTGCTGGTCAGTTAAATGACTTGTCAACG
GTTTTTCGTTTAGCTCAGGAAAACCTTGCGCAGGAAAAAAATCGTTTGGCTAGTATTTTGTCTTATATGACTGATGGTGT
CTTGGCTACTGACCGTTCTGGAAATATCACCATGATTAACCAAACAGCTCAGCAGCAACTTAATCTGGAACGCGAAGAAG
CTCTTGGAATGAATATTGTTGATATTCTTGGGGATGATAGCGATTATAGTTACCATGATTTGGTTTCTAAGACACCTGAG
ATTGTTCTAAATCGTCGTGATGAGACAGGTGAATTTATCACTTTGCGAATTCGTTTTGCGCTGAATCGTCGTGATAGTGG
CTTTATCTCAGGGTTAATTGCTGTTTTACATGATACAACGGAACAAGAAAAAGAAGACCGTGAACGTCGTTTATTCGTAT
CAAATGTTAGTCACGAATTGCGTACACCGTTGACATCTGTGAAATCATATTTGGAAGCTTTGGATGAAGGTGCCCTTAAA
GAAGATATTGCACCAAGTTTTATTAAAGTTTCTCTTGATGAAACAAACCGCATGATTCGAATGATTTCTGATTTGCTCAA
TTTGTCTCGAATTGATAATCAGACTGTTCAGCTTGAAGTTGAAATGACTAACTTTACAGCATTTATGACGTCAATTTTAA
ACCGTTTTGACCAAATTAAGAGTCAACACACTGTCGCTGGTAAGCAGTACGAGATTGTCAGAGATTATCCAATCAAGTCT
ATCTGGTTAGAAATTGACCCAGATAAAATGACGCAAGTTCTGGATAATATCCTTAATAATGCAATTAAGTATTCGCCAGA
TGGTGGTAAAATCACTGTCAGCATGAAGACGACTGAGACACAGTTGATTATTTCAATTTCTGATGAAGGTCTTGGTATTC
CTAAGAAAGATTTGCCACTAATCTTTGACCGATTCTATCGTGTTGACAAGGCTAGAAGTCGTGCTCAAGGTGGTTCAGGA
CTTGGCCTTGCGATTGCAAAAGAAATTGTTAAACAACACAAAGGATTTATTTGGGCTCAAAGTACTTATGGAAAAGGCTC
AACCTTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGACGAATGGGAGGATGACGAGGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-189)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.627

92.222

0.707
  micB Streptococcus pneumoniae Cp1015

66.038

94.222

0.622