Detailed information NTG0469796

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: H1R75_RS00340
• Genome accession: NZ_CP059471
• Coordinates: 50283..51191 (+)
• Length: 302 a.a.
• NCBI ID: WP_029876011.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain MDC1
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 45283..56191

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1R75_RS00315 (H1R75_00315)	purD	45427..46689 (+)	1263	WP_094141244.1	phosphoribosylamine--glycine ligase	-
H1R75_RS00320 (H1R75_00320)	-	46679..47128 (+)	450	WP_182001448.1	DUF523 domain-containing protein	-
H1R75_RS00325 (H1R75_00325)	purE	47128..47616 (+)	489	WP_021141395.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
H1R75_RS00330 (H1R75_00330)	purK	47603..48694 (+)	1092	WP_021141396.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
H1R75_RS00335 (H1R75_00335)	purB	48835..50133 (+)	1299	WP_024344772.1	adenylosuccinate lyase	-
H1R75_RS00340 (H1R75_00340)	comR	50283..51191 (+)	909	WP_029876011.1	helix-turn-helix domain-containing protein	Regulator
H1R75_RS00345 (H1R75_00345)	ruvB	51364..52362 (+)	999	WP_021141399.1	Holliday junction branch migration DNA helicase RuvB	-
H1R75_RS00350 (H1R75_00350)	-	52572..53003 (+)	432	WP_033152105.1	low molecular weight protein-tyrosine-phosphatase	-
H1R75_RS00355 (H1R75_00355)	-	53020..53400 (+)	381	WP_021141401.1	MORN repeat-containing protein	-
H1R75_RS00360 (H1R75_00360)	-	53397..55190 (+)	1794	WP_182001449.1	acyltransferase family protein	-

Sequence

Protein

• Length: 302 a.a.
• Molecular weight: 35531.41 Da
• Isoelectric Point: 4.6281

>NTDB_id=469796 H1R75_RS00340 WP_029876011.1 50283..51191(+) (comR) [Streptococcus equinus strain MDC1]
MEVKKFGNKIRILREKKGISREEFCGDETELSVRQLARIELNQSIPNLSKAQFIANRLGVKLGTLTDGDSLELPKRYKEL
KYLLLRTPTYGDQERVDRKNDYFDEISENYYDIIPEEEKLIIDCLQSKFDVHFSDDVNFGDGILNDYFDQVIRKETFNIN
DLILIDLYCVCMASAKAYTGIYSLDIYDNLMDCLLNQSHVTPETSLILNNVLLNNIALAFQFEREDYVYQVIKISDRIMT
EIHDFQRRPILSLVEWKYYLKFKHDYDSAKQSFTNATLFARLIGDVYLENKLKEEWEFDTTT

Nucleotide

• Length: 909 bp

>NTDB_id=469796 H1R75_RS00340 WP_029876011.1 50283..51191(+) (comR) [Streptococcus equinus strain MDC1]
ATGGAAGTGAAAAAATTTGGGAACAAAATTCGTATTTTGCGGGAGAAAAAGGGAATCTCACGCGAAGAATTCTGTGGGGA
CGAGACCGAATTATCTGTACGACAACTAGCACGAATTGAGCTAAATCAATCGATACCTAACCTAAGTAAAGCCCAATTCA
TTGCTAATCGCCTTGGCGTAAAACTTGGAACCCTGACAGACGGCGATAGCTTAGAATTACCGAAGCGGTATAAAGAGCTG
AAGTATTTGTTGCTTAGGACACCGACATATGGCGATCAAGAGAGAGTTGATCGGAAAAATGATTATTTTGATGAGATATC
AGAGAATTATTACGATATTATTCCTGAAGAAGAGAAACTCATCATAGATTGTTTACAGTCAAAATTTGATGTTCATTTTA
GTGACGACGTAAATTTTGGTGATGGTATTTTAAATGATTATTTTGATCAAGTTATTCGTAAAGAGACTTTTAATATCAAT
GATTTAATTTTGATTGATCTTTACTGTGTATGCATGGCATCCGCTAAAGCGTATACCGGAATTTACAGTTTGGATATTTA
TGATAATTTGATGGATTGTTTATTAAATCAAAGTCATGTTACGCCGGAGACTAGTTTGATTTTAAATAATGTGTTGTTAA
ATAATATTGCTCTGGCTTTTCAATTTGAACGAGAAGACTACGTTTATCAAGTGATTAAAATAAGCGATAGGATTATGACT
GAGATTCATGATTTTCAACGTCGCCCAATTTTAAGTTTAGTTGAATGGAAATATTATTTGAAGTTTAAACATGATTATGA
CAGTGCAAAACAGTCTTTTACCAATGCAACTTTATTTGCAAGATTAATTGGTGATGTTTACTTAGAGAACAAACTTAAAG
AAGAATGGGAATTCGATACAACAACATGA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (10-63)

• ComR tetratricopeptide (ComR_TPR) (74-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	82.23	95.033	0.781
comR	Streptococcus mutans UA159	52.843	99.007	0.523
comR	Streptococcus pyogenes MGAS8232	50	100	0.5
comR	Streptococcus pyogenes MGAS315	44.631	98.675	0.44
comR	Streptococcus suis D9	38.614	100	0.387
comR	Streptococcus suis P1/7	38	99.338	0.377
comR	Streptococcus suis 05ZYH33	38	99.338	0.377