NTDB

Overview

Name	comEA	Type	Machinery gene
Locus tag	H0A38_RS09205	Genome accession	NZ_CP059048
Coordinates	1901433..1902080 (-)	Length	215 a.a.
NCBI ID	WP_058203544.1	Uniprot ID	A0AB35KBC8
Organism	Lactococcus lactis strain LAC460
Function	dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1896433..1907080

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0A38_RS09180 (H0A38_09125)	atpF	1896502..1897008 (-)	507	WP_226319330.1	F0F1 ATP synthase subunit B	-
H0A38_RS09185 (H0A38_09130)	atpB	1897023..1897736 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
H0A38_RS09190 (H0A38_09135)	-	1897781..1897996 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
H0A38_RS09195 (H0A38_09140)	-	1898181..1898957 (-)	777	WP_004255244.1	alpha/beta hydrolase family protein	-
H0A38_RS09200 (H0A38_09145)	comEC	1899242..1901452 (-)	2211	WP_129881048.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
H0A38_RS09205 (H0A38_09150)	comEA	1901433..1902080 (-)	648	WP_058203544.1	ComEA family DNA-binding protein	Machinery gene
H0A38_RS09210 (H0A38_09155)	-	1902140..1903501 (-)	1362	WP_129881049.1	ABC transporter permease	-
H0A38_RS09215 (H0A38_09160)	-	1903498..1904430 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
H0A38_RS09220 (H0A38_09165)	-	1904535..1904933 (-)	399	WP_023188528.1	hypothetical protein	-
H0A38_RS09225 (H0A38_09170)	-	1905037..1905600 (-)	564	WP_129881050.1	GNAT family N-acetyltransferase	-
H0A38_RS09230 (H0A38_09175)	-	1905773..1906951 (-)	1179	WP_129881051.1	SLC13 family permease	-

Sequence

Protein

Download Length: 215 a.a. Molecular weight: 23634.80 Da Isoelectric Point: 4.8659

                                >NTDB_id=466769 H0A38_RS09205 WP_058203544.1 1901433..1902080(-) (comEA) [Lactococcus lactis strain LAC460]

MDKILEKVKEYWKMIVLIVCGLIAGGIFYVLTNGQKPTTNLSVENLSSVSRQSSVSKFSEPNEKSVSKIMVDLKGAVTKP

NVYQISPDERLVDLIKEAGGFTDQADQKSINLSAKLKDEEVIYVPKIGENSSTENTDSSANSVTSQVSTTTEKININQAD

VTELQKLTGVGQKKAQDIIDFRTKNGDFKSLEDLGKVSGFGDKTLEKLKDELCFE

Nucleotide

Download Length: 648 bp

                                >NTDB_id=466769 H0A38_RS09205 WP_058203544.1 1901433..1902080(-) (comEA) [Lactococcus lactis strain LAC460]

ATGGATAAGATTTTAGAAAAAGTAAAAGAATATTGGAAAATGATTGTTTTAATTGTTTGTGGGCTCATTGCTGGTGGGAT

TTTTTACGTTTTAACCAACGGTCAAAAGCCAACTACAAATCTGTCAGTAGAAAATTTAAGTTCTGTCAGCAGGCAAAGCT

CTGTCAGTAAATTTAGTGAACCTAATGAAAAATCTGTCAGTAAAATTATGGTTGATTTAAAAGGTGCGGTAACAAAGCCT

AATGTCTATCAAATTTCGCCAGATGAACGTCTAGTTGATTTAATTAAGGAAGCTGGTGGTTTTACTGACCAAGCTGACCA

GAAATCAATTAATCTGTCAGCAAAATTAAAAGATGAAGAAGTAATTTATGTCCCAAAAATTGGTGAAAATTCAAGCACAG

AAAATACTGACAGCTCTGCTAATTCTGTCACTAGTCAAGTCTCAACAACCACTGAAAAAATAAATATCAATCAAGCAGAT

GTGACTGAACTACAAAAATTAACAGGTGTTGGTCAGAAAAAAGCTCAAGACATCATTGATTTTCGGACGAAAAATGGTGA

TTTCAAATCACTTGAAGACTTGGGAAAAGTTTCTGGTTTTGGAGATAAAACACTAGAAAAATTGAAAGATGAGTTGTGTT

TTGAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(151-212)

SLBB domain (SLBB)

(70-125)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comEA	Lactococcus lactis subsp. cremoris KW2	74.771	100	0.758
comEA/celA/cilE	Streptococcus mitis SK321	44.444	100	0.447
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	43.119	100	0.437
comEA/celA/cilE	Streptococcus pneumoniae Rx1	41.096	100	0.419
comEA/celA/cilE	Streptococcus pneumoniae D39	41.096	100	0.419
comEA/celA/cilE	Streptococcus pneumoniae R6	41.096	100	0.419
comEA/celA/cilE	Streptococcus mitis NCTC 12261	41.284	100	0.419
comEA	Latilactobacillus sakei subsp. sakei 23K	36.123	100	0.381

Detailed information NTG0466769