Detailed information NTG0466751

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: H0A38_RS02355
• Genome accession: NZ_CP059048
• Coordinates: 466986..469232 (+)
• Length: 748 a.a.
• NCBI ID: WP_129881449.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain LAC460
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 461986..474232

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0A38_RS02335 (H0A38_02335)	rpoD	462764..463924 (+)	1161	WP_026138868.1	RNA polymerase sigma factor RpoD	-
H0A38_RS02340 (H0A38_02340)	-	464039..464782 (+)	744	WP_010905438.1	MurR/RpiR family transcriptional regulator	-
H0A38_RS02345 (H0A38_02345)	-	464947..466314 (+)	1368	WP_165379815.1	MFS transporter	-
H0A38_RS02350 (H0A38_02350)	-	466597..466935 (+)	339	WP_012897282.1	hypothetical protein	-
H0A38_RS02355 (H0A38_02355)	clpC	466986..469232 (+)	2247	WP_129881449.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
H0A38_RS02360 (H0A38_02360)	-	469522..469992 (-)	471	WP_003130820.1	Rrf2 family transcriptional regulator	-
H0A38_RS02365 (H0A38_02365)	gap	470165..471178 (+)	1014	WP_003130818.1	type I glyceraldehyde-3-phosphate dehydrogenase	-
H0A38_RS02370 (H0A38_02370)	def	471321..471956 (-)	636	WP_003130816.1	peptide deformylase	-
H0A38_RS02375 (H0A38_02375)	-	472104..472565 (+)	462	WP_306171264.1	RNA pyrophosphohydrolase	-

Sequence

Protein

• Length: 748 a.a.
• Molecular weight: 83105.83 Da
• Isoelectric Point: 4.7369

>NTDB_id=466751 H0A38_RS02355 WP_129881449.1 466986..469232(+) (clpC) [Lactococcus lactis strain LAC460]
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALHGQDFNGAAST
QTPPTQTGGRGPRGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAETKKNEATQAEDFEKAAHFRDQITKLRELQNQEVS
DDEIPVITEKDIEQIVEQKTHIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKIAKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKELV
ADLIDDKIVISNQAQEAAETTDEEVPAE

Nucleotide

• Length: 2247 bp

>NTDB_id=466751 H0A38_RS02355 WP_129881449.1 466986..469232(+) (clpC) [Lactococcus lactis strain LAC460]
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGCGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAATGGAA
ATTCTGATGAACCATTTAATCCATTTAATGATATCTTTAGTGCTTTGCACGGTCAAGATTTTAATGGAGCAGCAAGCACT
CAAACTCCACCAACACAAACAGGTGGACGTGGTCCGCGCGGTCCACAAAATCCTCGGGCAAAACAACCTAAAGGAATGTT
AGAAGAATTTGGAATTAACATCACAGAGTCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATTA
AACGTGTCATTGAGATTTTAAATCGTAGGACTAAGAATAATCCTGTATTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCGCAAAAAATTGTGGACGGAGATGTGCCGCAAAAACTACAAAATAAAGAAGTGATTCGTCTTGA
TGTTGTTTCTCTTGTTCAAGGAACAGGAATTCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTGATTATGTTTATTGATGAAATTCATGAAATTGTTGGTGCTGGTTCTGCCGGTGATGGCAATATGGAT
GCAGGAAATATCCTAAAACCTGCGCTTGCGCGTGGTGAGCTTCAATTGGTCGGAGCAACAACGCTCAATGAATATCGCAT
CATTGAAAAAGATGCTGCGCTTGAACGCCGGATGCAACCAGTTAAAGTCGATGAACCATCAGTTGATGAAACAATTACTA
TTTTGCGAGGTATTCAAGCACGTTATGAAGATTATCATCACGTGAAATACACTGATGAGGCTATTGAAGCAGCCGCTCAT
TTGTCAAATCGTTACATTCAAGACCGTTTCTTACCAGATAAAGCCATTGACCTTTTGGATGAGTCTGGTTCTAAGAAAAA
TCTAACCTTGAAATTTGTTGATCCTGAAGATATTAATCGTCGGATTGCGGATGCAGAAACGAAGAAAAATGAAGCAACAC
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCACTAAACTTCGTGAATTACAAAATCAAGAAGTTTCA
GATGATGAAATTCCTGTCATCACTGAAAAAGATATTGAACAAATTGTTGAGCAAAAAACACATATTCCAGTTGGTGATTT
GAAAGAAAAAGAACAAACCCAATTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAGGATGAAGCAGTGG
ATAAGATTGCTAAAGCTATCCGTCGTTCTCGTGTGGGACTTGGTAAACCTAATCGTCCAATTGGTTCTTTCCTTTTCGTT
GGTCCAACAGGTGTTGGTAAAACAGAACTTGCTAAACAATTGGCTAAAGAATTATTTGGCTCAAGTGAAAGTATGATTCG
TTTTGACATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTAATTGGAGCCCCTCCAGGATATGTGGGTTATGAAG
AAGCTGGTCAATTGACTGAACGTGTTCGTCGTAATCCCTACAGTTTGATTTTATTAGATGAAATCGAAAAAGCACATCCA
GATGTGATGCACATGTTCTTGCAAATTCTTGAAGATGGACGTCTGACAGACGCACAAGGACGGACAGTATCCTTTAAAGA
TAGTTTGATTATTATGACTTCTAATGCCGGAACTGGTAAAGTTGAAGCCTCTGTCGGATTTGGTGCTGCTCGTGAGGGAC
GAACTAAATCAGTGCTTGGTCAGCTTGGCGATTTCTTTAGCCCTGAATTCATGAACCGTTTTGACGGAATAATTGAATTC
TCTGCTTTGAGCAAAGAAAATCTCCTTAAAATTGTTGATTTGATGCTTGATGAAGTCAACGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCAGCAAAAGAAAAATTAGTTGATCTAGGTTACAATCCAGCAATGGGTGCAAGACCAC
TTCGTAGAACAATTCAAGAAAATATCGAAGATTCAATTGCTGACTTCTATATTGAACACCCTGAATACAAAGAATTGGTT
GCTGATTTGATTGATGATAAAATTGTTATCTCTAATCAAGCTCAAGAAGCAGCAGAAACGACTGATGAAGAAGTTCCTGC
TGAATAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (149-268)

• AAA domain (Cdc48 subfamily) (AAA_2) (472-635)

• AAA lid domain (AAA_lid_9) (287-386)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (643-713)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	97.995	100	0.98
clpE	Streptococcus mutans UA159	76.026	100	0.767
clpE	Streptococcus pneumoniae Rx1	75.543	98.396	0.743
clpE	Streptococcus pneumoniae D39	75.543	98.396	0.743
clpE	Streptococcus pneumoniae R6	75.543	98.396	0.743
clpE	Streptococcus pneumoniae TIGR4	75.543	98.396	0.743
clpC	Bacillus subtilis subsp. subtilis str. 168	51.584	88.636	0.457
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.635	81.952	0.39
clpC	Streptococcus pneumoniae Rx1	46.635	83.422	0.389
clpC	Streptococcus pneumoniae D39	46.635	83.422	0.389
clpC	Streptococcus pneumoniae TIGR4	46.635	83.422	0.389
clpC	Streptococcus thermophilus LMD-9	46.104	82.353	0.38
clpC	Streptococcus thermophilus LMG 18311	45.942	82.353	0.378
clpC	Streptococcus mutans UA159	45.631	82.62	0.377