Detailed information NTG0458583

Bioinformatically predicted

Overview

• Name: comD/comD2
• Type: Regulator
• Locus tag: I6J15_RS04180
• Genome accession: NZ_CP068056
• Coordinates: 808386..809219 (+)
• Length: 277 a.a.
• NCBI ID: WP_111713004.1
• Uniprot ID: -
• Organism: Streptococcus lutetiensis strain FDAARGOS_1158
• Function: phosphorylation of ComE (predicted from homology) Competence regulation

Genomic Context

Location: 803386..814219

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J15_RS09060	-	803754..803831 (+)	78	Protein_756	hypothetical protein	-
I6J15_RS04150 (I6J15_04150)	-	803968..804738 (+)	771	WP_003066600.1	TatD family hydrolase	-
I6J15_RS04155 (I6J15_04155)	rnmV	804731..805300 (+)	570	WP_167394768.1	ribonuclease M5	-
I6J15_RS04160 (I6J15_04160)	rsmA	805423..806295 (+)	873	WP_021143191.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
I6J15_RS04165 (I6J15_04165)	-	806702..806851 (+)	150	WP_020917491.1	hypothetical protein	-
I6J15_RS04170 (I6J15_04170)	-	806864..807169 (+)	306	WP_020917490.1	bacteriocin immunity protein	-
I6J15_RS04175 (I6J15_04175)	-	807197..807490 (+)	294	WP_020917489.1	bacteriocin immunity protein	-
I6J15_RS04180 (I6J15_04180)	comD/comD2	808386..809219 (+)	834	WP_111713004.1	sensor histidine kinase	Regulator
I6J15_RS09065	comE/comE2	809777..810004 (+)	228	WP_233422877.1	hypothetical protein	Regulator
I6J15_RS09070	comE/comE2	809989..810369 (+)	381	WP_267895290.1	LytR/AlgR family response regulator transcription factor	Regulator
I6J15_RS09290	comE/comE2	810422..810508 (+)	87	WP_250543510.1	hypothetical protein	Regulator
I6J15_RS04195 (I6J15_04195)	rsgA	810826..811698 (+)	873	WP_058832824.1	ribosome small subunit-dependent GTPase A	-
I6J15_RS04200 (I6J15_04200)	rpe	811705..812367 (+)	663	WP_020917487.1	ribulose-phosphate 3-epimerase	-
I6J15_RS04205 (I6J15_04205)	-	812360..812992 (+)	633	WP_020917486.1	thiamine diphosphokinase	-

Sequence

Protein

• Length: 277 a.a.
• Molecular weight: 31707.21 Da
• Isoelectric Point: 4.6102

>NTDB_id=458583 I6J15_RS04180 WP_111713004.1 808386..809219(+) (comD/comD2) [Streptococcus lutetiensis strain FDAARGOS_1158]
MVSYFLFMDAVAIVKPFHNTVNDAIRGIVAFIYLILLFVFLFYLNFRHGQEQKNELLRNQEMELAALENCSKHVESLYQE
VRSFRHDYANVLMSLKVGIDQGNLDDIKKIYNEITANSTKLVKNNKFDLTRLANIIDSGVKSFMSAKFLQAENQGIAISL
EVAEKMENPSMPLIYYIRILSILFDNAIEAALESETPEISVANFYQDGNFVFMIENSTKEKSVDLTKIFERGYSTKGENR
GLGLATLMDFQDDDENLSVEIRSSDYTFTQVVRIFDA

Nucleotide

• Length: 834 bp

>NTDB_id=458583 I6J15_RS04180 WP_111713004.1 808386..809219(+) (comD/comD2) [Streptococcus lutetiensis strain FDAARGOS_1158]
ATGGTCTCTTATTTTTTATTCATGGATGCCGTTGCTATTGTAAAACCTTTTCATAATACTGTTAACGATGCAATAAGGGG
AATTGTTGCTTTCATTTATCTCATCCTTCTTTTTGTCTTCCTCTTTTATCTTAATTTCCGTCATGGGCAAGAGCAGAAAA
ATGAATTGCTTCGTAACCAGGAAATGGAATTGGCGGCCTTGGAAAATTGTAGCAAGCACGTGGAGAGTTTGTATCAGGAG
GTTCGCAGTTTCAGGCATGACTACGCTAATGTCCTGATGAGTTTAAAGGTTGGAATTGATCAAGGCAATCTTGATGACAT
CAAGAAAATTTACAACGAAATCACAGCCAATTCGACGAAGCTAGTCAAGAATAATAAATTTGACCTGACTCGCTTGGCTA
ACATCATAGACAGCGGCGTCAAAAGCTTCATGTCAGCTAAATTTTTGCAAGCTGAAAATCAAGGGATTGCAATTAGTCTA
GAAGTCGCCGAAAAAATGGAAAATCCTAGCATGCCATTAATTTATTACATTCGAATTTTGTCGATTCTGTTTGATAATGC
CATAGAAGCCGCTTTGGAGTCAGAAACTCCAGAAATCTCAGTCGCTAATTTTTACCAAGATGGTAACTTTGTTTTCATGA
TTGAGAATTCAACTAAGGAAAAATCAGTGGATTTAACTAAGATTTTTGAGCGTGGCTACTCAACTAAGGGAGAAAATCGT
GGACTTGGTCTAGCCACACTAATGGATTTCCAAGATGACGACGAAAATCTGTCAGTTGAAATTCGCAGCTCAGATTACAC
ATTTACACAAGTTGTCCGAATTTTTGATGCATAA

Domains

Predicted by InterProScan.

• GHKL domain (HATPase_c_5) (177-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comD/comD2	Streptococcus equinus JB1	88.087	100	0.881
comD/comD3	Streptococcus equinus JB1	83.026	97.834	0.812
comD/blpH	Streptococcus mutans UA159	39.051	98.917	0.386
comD/comD1	Streptococcus equinus JB1	46.32	83.394	0.386