Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HV559_RS06200 Genome accession   NZ_CP055306
Coordinates   1279031..1280224 (+) Length   397 a.a.
NCBI ID   WP_176809847.1    Uniprot ID   A0A7D5HQM8
Organism   Mannheimia pernigra strain BNO311     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1274031..1285224
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HV559_RS06175 (HV559_06175) - 1274728..1275222 (+) 495 WP_159629590.1 dihydrofolate reductase -
  HV559_RS06180 (HV559_06180) - 1275350..1275583 (+) 234 WP_159629593.1 YgjV family protein -
  HV559_RS06185 (HV559_06185) radA 1275622..1277001 (-) 1380 WP_176808292.1 DNA repair protein RadA Machinery gene
  HV559_RS06190 (HV559_06190) pilA 1277182..1277625 (+) 444 WP_176809845.1 prepilin peptidase-dependent pilin Machinery gene
  HV559_RS06195 (HV559_06195) pilB 1277647..1279047 (+) 1401 WP_176809846.1 GspE/PulE family protein Machinery gene
  HV559_RS06200 (HV559_06200) pilC 1279031..1280224 (+) 1194 WP_176809847.1 type II secretion system F family protein Machinery gene
  HV559_RS06205 (HV559_06205) - 1280227..1280883 (+) 657 WP_176808296.1 prepilin peptidase -
  HV559_RS06210 (HV559_06210) coaE 1280915..1281553 (+) 639 WP_176809848.1 dephospho-CoA kinase -
  HV559_RS06215 (HV559_06215) yacG 1281535..1281720 (+) 186 WP_159629615.1 DNA gyrase inhibitor YacG -
  HV559_RS06220 (HV559_06220) holA 1281721..1282743 (-) 1023 WP_176809849.1 DNA polymerase III subunit delta -
  HV559_RS06225 (HV559_06225) lptE 1282784..1283272 (-) 489 WP_176808298.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 397 a.a.        Molecular weight: 45512.10 Da        Isoelectric Point: 9.4575

>NTDB_id=457531 HV559_RS06200 WP_176809847.1 1279031..1280224(+) (pilC) [Mannheimia pernigra strain BNO311]
MAKIYEYHWKAVDRFQQKRKGSRLSSSREELESMLLMKGYEQIRINRNFVLSQNPKREQISQFISQLALLVNSAISLKQA
LSMILQNCRNIKMYQWLSELILLIENGYSFSQSLEKQDKFIANQELQLIKMGEQSGKLGIILTNLAKSRAKSDKLAKKVK
KILFYPAIVLFISLSLSLGLLIFIVPQFAELYGTKEKALPLITEILFSLSQCLIEQKHLLLSLLLAVVFFLFFAKRENGF
VRLKMALLSKLPVFRQIIQQARIVFFSQNMALMLNAHIPLDLVLKSFLSEKSDDPILQKEVEFMLNLLQQGYPFSQGINP
NVFGLDMPQMIEIGEQSGNVANICEHISEMYQQKLDYQIDILSQLLEPMLMLLMGIIVGTIIVGLYLPIFDMGSLVE

Nucleotide


Download         Length: 1194 bp        

>NTDB_id=457531 HV559_RS06200 WP_176809847.1 1279031..1280224(+) (pilC) [Mannheimia pernigra strain BNO311]
ATGGCGAAAATCTATGAATACCATTGGAAAGCGGTTGATCGTTTCCAACAAAAACGTAAAGGCAGCCGATTATCTAGCAG
CCGAGAAGAGCTTGAAAGTATGTTGCTAATGAAAGGTTATGAGCAGATTCGCATTAATCGAAACTTCGTTTTATCTCAAA
ATCCGAAAAGAGAGCAGATCAGCCAATTTATTTCCCAGCTTGCGTTATTAGTGAATTCTGCTATATCGTTAAAACAGGCT
CTTTCGATGATTTTACAAAACTGCCGAAATATTAAAATGTATCAATGGCTAAGCGAGCTCATTTTGCTGATTGAAAATGG
TTATTCTTTTTCACAATCATTAGAGAAACAAGATAAATTTATTGCTAATCAAGAACTTCAACTGATTAAAATGGGCGAGC
AAAGCGGAAAACTAGGTATCATCTTAACGAATTTGGCGAAAAGCCGAGCTAAGTCTGATAAGTTAGCTAAAAAAGTGAAG
AAAATCCTGTTTTATCCTGCGATTGTATTGTTTATTTCCCTGTCTCTTTCTCTCGGATTGTTGATCTTCATTGTGCCCCA
GTTTGCAGAACTTTACGGCACAAAAGAGAAAGCCTTACCACTGATTACGGAAATACTATTTTCTCTTTCCCAGTGTTTGA
TTGAACAGAAGCATCTTCTACTTAGTTTATTACTAGCGGTCGTTTTTTTCCTCTTTTTTGCAAAAAGAGAGAACGGGTTT
GTGAGGTTAAAAATGGCGTTATTGTCTAAACTCCCTGTATTTCGACAAATCATACAGCAAGCCCGTATTGTCTTTTTTAG
CCAAAATATGGCTTTAATGTTGAATGCTCATATTCCGTTAGATTTGGTATTAAAATCCTTTTTATCTGAAAAAAGCGACG
ATCCTATATTACAAAAAGAGGTTGAATTTATGCTAAATCTCTTGCAACAAGGCTACCCATTTTCGCAAGGCATTAATCCA
AATGTGTTTGGCTTAGATATGCCACAAATGATCGAAATCGGCGAGCAAAGCGGCAACGTTGCCAACATATGCGAACATAT
TAGCGAGATGTACCAACAAAAACTGGATTATCAAATTGATATACTTTCTCAGTTATTAGAGCCAATGTTGATGTTACTGA
TGGGAATAATTGTGGGGACTATTATTGTCGGTTTATATCTACCCATTTTTGATATGGGAAGTTTAGTGGAGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-388)

Type II secretion system (T2SS), protein F (T2SSF)

(63-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7D5HQM8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

56.25

100

0.567
  pilC Haemophilus influenzae Rd KW20

40.898

100

0.413
  pilC Haemophilus influenzae 86-028NP

40.15

100

0.406