Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   I6H73_RS00050 Genome accession   NZ_CP066073
Coordinates   14743..15774 (+) Length   343 a.a.
NCBI ID   WP_015057201.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1016     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9743..20774
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H73_RS00040 (I6H73_00040) - 13420..13785 (+) 366 WP_003055257.1 DUF1033 family protein -
  I6H73_RS00045 (I6H73_00045) comGA/cglA 13866..14807 (+) 942 WP_003055265.1 competence type IV pilus ATPase ComGA Machinery gene
  I6H73_RS00050 (I6H73_00050) comGB 14743..15774 (+) 1032 WP_015057201.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6H73_RS00055 (I6H73_00055) comGC 15776..16102 (+) 327 WP_003055259.1 competence type IV pilus major pilin ComGC Machinery gene
  I6H73_RS00060 (I6H73_00060) - 16139..17593 (-) 1455 WP_003055278.1 recombinase family protein -
  I6H73_RS00065 (I6H73_00065) - 17730..18221 (-) 492 WP_003055290.1 hypothetical protein -
  I6H73_RS00070 (I6H73_00070) - 18232..19002 (-) 771 WP_003055282.1 XRE family transcriptional regulator -
  I6H73_RS00075 (I6H73_00075) - 19203..19406 (+) 204 WP_003058516.1 helix-turn-helix transcriptional regulator -
  I6H73_RS00080 (I6H73_00080) - 19695..19844 (+) 150 WP_003058552.1 hypothetical protein -
  I6H73_RS00085 (I6H73_00085) - 19884..20231 (+) 348 WP_003058582.1 hypothetical protein -
  I6H73_RS00090 (I6H73_00090) - 20492..20740 (+) 249 WP_003058590.1 hypothetical protein -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 38953.34 Da        Isoelectric Point: 9.2055

>NTDB_id=453610 I6H73_RS00050 WP_015057201.1 14743..15774(+) (comGB) [Streptococcus dysgalactiae strain FDAARGOS_1016]
MTFLQRDISVRSKQGLKKLSSKEQYKLIQLLANLLLTGFNLAEIIAFLTKSHLIPEPYVLRMEEALLKGRGLADMLAGIG
FSDAILTQISLADGHGNIETTLVNIQGYLNQMAKLKRKTIEVVTYPIILLVFLFVMILGLRHYVMPQLEAQNQLTIFLTH
FPAIFFGIILFIGVLLGGIWLHWRSQSRLKLFTHFSAYPVLGKLLQQYLTAYYAREWGTLIGQGLELPVILDIMAMEKSL
FMQELAEDIRVSLLAGQAFHDKVATYPFFKKELSLMITYGEIKSKLGSELEIYAQESWTQFFSQLHQATQFIQPIIFLVI
ALTIVMIYAAILLPIYQNMGGVL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=453610 I6H73_RS00050 WP_015057201.1 14743..15774(+) (comGB) [Streptococcus dysgalactiae strain FDAARGOS_1016]
ATGACCTTCTTGCAGCGGGACATCTCAGTCCGGAGCAAGCAAGGTTTGAAAAAATTATCCAGTAAGGAACAATACAAACT
AATTCAGCTATTAGCTAACCTTTTGTTAACAGGATTTAACTTGGCTGAGATAATAGCTTTCTTAACAAAAAGTCATTTGA
TTCCCGAGCCCTATGTTCTCCGCATGGAAGAAGCACTCTTAAAAGGTCGAGGGCTGGCAGATATGTTAGCTGGGATAGGT
TTTTCGGATGCTATTTTAACTCAAATTAGTTTAGCAGATGGTCACGGAAACATTGAGACGACGCTTGTTAATATTCAGGG
CTATCTCAACCAAATGGCTAAACTTAAACGAAAAACCATTGAAGTCGTCACCTATCCGATTATTCTCCTGGTATTTCTTT
TTGTGATGATATTAGGGTTAAGGCATTATGTTATGCCTCAATTAGAAGCTCAAAATCAGCTTACTATTTTTCTGACTCAT
TTTCCAGCTATTTTCTTTGGTATTATCCTTTTTATAGGTGTGCTGTTAGGGGGAATTTGGCTGCATTGGCGATCGCAAAG
TCGCCTCAAGCTTTTTACTCACTTCAGTGCTTATCCTGTTTTAGGGAAACTCTTACAACAGTATCTGACGGCTTATTATG
CTAGAGAATGGGGAACATTGATTGGACAGGGACTTGAATTACCAGTCATTCTGGATATTATGGCCATGGAGAAATCTTTA
TTCATGCAAGAATTGGCTGAAGATATTCGAGTTAGTTTATTGGCAGGACAAGCTTTTCATGATAAGGTAGCTACCTATCC
TTTCTTTAAAAAAGAGTTAAGTTTGATGATTACTTATGGAGAGATTAAATCCAAGTTAGGAAGTGAACTAGAGATTTATG
CTCAAGAGAGTTGGACTCAGTTTTTCAGCCAACTTCATCAAGCAACTCAGTTTATTCAACCGATTATCTTTTTAGTGATT
GCTCTGACGATTGTCATGATTTATGCAGCAATTTTATTACCAATTTATCAAAATATGGGAGGCGTTTTATAA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(28-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Streptococcus mutans UA140

53.392

98.834

0.528
  comGB Streptococcus mutans UA159

53.392

98.834

0.528
  comGB Streptococcus gordonii str. Challis substr. CH1

48.673

98.834

0.481
  comGB/cglB Streptococcus mitis NCTC 12261

45.97

97.668

0.449
  comGB/cglB Streptococcus mitis SK321

45.345

97.085

0.44
  comGB/cglB Streptococcus pneumoniae Rx1

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae D39

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae R6

43.844

97.085

0.426
  comGB/cglB Streptococcus pneumoniae TIGR4

43.844

97.085

0.426
  comGB Lactococcus lactis subsp. cremoris KW2

42.773

98.834

0.423