Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   I6H73_RS00045 Genome accession   NZ_CP066073
Coordinates   13866..14807 (+) Length   313 a.a.
NCBI ID   WP_003055265.1    Uniprot ID   A0ABU0A7H1
Organism   Streptococcus dysgalactiae strain FDAARGOS_1016     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 8866..19807
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H73_RS00035 (I6H73_00035) rpoC 9577..13218 (+) 3642 WP_003055274.1 DNA-directed RNA polymerase subunit beta' -
  I6H73_RS00040 (I6H73_00040) - 13420..13785 (+) 366 WP_003055257.1 DUF1033 family protein -
  I6H73_RS00045 (I6H73_00045) comGA/cglA 13866..14807 (+) 942 WP_003055265.1 competence type IV pilus ATPase ComGA Machinery gene
  I6H73_RS00050 (I6H73_00050) comGB 14743..15774 (+) 1032 WP_015057201.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6H73_RS00055 (I6H73_00055) comGC 15776..16102 (+) 327 WP_003055259.1 competence type IV pilus major pilin ComGC Machinery gene
  I6H73_RS00060 (I6H73_00060) - 16139..17593 (-) 1455 WP_003055278.1 recombinase family protein -
  I6H73_RS00065 (I6H73_00065) - 17730..18221 (-) 492 WP_003055290.1 hypothetical protein -
  I6H73_RS00070 (I6H73_00070) - 18232..19002 (-) 771 WP_003055282.1 XRE family transcriptional regulator -
  I6H73_RS00075 (I6H73_00075) - 19203..19406 (+) 204 WP_003058516.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35224.31 Da        Isoelectric Point: 7.0642

>NTDB_id=453609 I6H73_RS00045 WP_003055265.1 13866..14807(+) (comGA/cglA) [Streptococcus dysgalactiae strain FDAARGOS_1016]
MVQALARSILKEAEQIQAQDIYILPKEDQYELLIRVGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
IDGDTLLSLRLSSVGNYRGQESLVIRLLHHQQRSLHYWFDGLKTVARQIGGRGLYLFAGPVGSGKTTLMHQLIADYYQGA
QVISIEDPVEIKNHQALQLQVNDSIGMTYDNLIKLSLRHRPDILIIGEIRDSQTARAVIRASLTGVLVFSTVHAKSISGV
YARLLELGVTRAELDNCLALVAYQRLLNGGALIDSTQTEFEHYSPNQWNQKIDDLLAAGHLSPEQARFEKIIQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=453609 I6H73_RS00045 WP_003055265.1 13866..14807(+) (comGA/cglA) [Streptococcus dysgalactiae strain FDAARGOS_1016]
ATGGTACAAGCATTAGCAAGATCTATTTTGAAAGAAGCTGAGCAGATTCAAGCTCAAGATATCTATATTTTGCCAAAGGA
AGATCAGTATGAGCTATTGATAAGGGTAGGAGATGAAAGGAGATTGGTGGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGACCGTTGGTGAGAAACGACGCTGTCAAGTCGGTTCTTGTGATTATGAT
ATCGATGGAGACACACTTTTGTCTCTACGCCTGTCTAGTGTTGGAAATTACCGTGGACAAGAGAGCCTAGTGATTCGGTT
ATTACATCATCAACAAAGAAGTTTACATTACTGGTTTGACGGACTGAAAACAGTTGCACGTCAGATTGGAGGCCGAGGAC
TCTATCTTTTTGCAGGTCCAGTCGGATCAGGCAAAACGACTTTGATGCACCAATTGATTGCTGATTATTATCAAGGAGCA
CAGGTCATTAGCATAGAAGATCCGGTGGAAATTAAAAATCATCAAGCGCTCCAATTACAAGTTAATGATAGTATTGGCAT
GACTTACGACAACTTGATCAAACTATCTTTACGGCATCGCCCTGATATTTTAATCATTGGTGAAATTCGAGACAGCCAGA
CAGCTAGAGCGGTTATTAGAGCAAGTTTAACAGGTGTCTTAGTATTTTCAACAGTTCATGCCAAAAGCATTTCTGGTGTT
TATGCCAGATTACTAGAACTAGGAGTGACAAGAGCAGAATTAGACAATTGTTTGGCTTTGGTTGCTTACCAACGATTGCT
TAATGGAGGAGCATTGATTGACTCAACTCAAACAGAATTTGAACACTACTCACCAAACCAATGGAATCAGAAAATTGATG
ACCTTCTTGCAGCGGGACATCTCAGTCCGGAGCAAGCAAGGTTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.701

99.361

0.623
  comGA Streptococcus mutans UA140

61.736

99.361

0.613
  comGA Streptococcus mutans UA159

61.736

99.361

0.613
  comGA Streptococcus gordonii str. Challis substr. CH1

61.415

99.361

0.61
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

60.45

99.361

0.601
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

60.129

99.361

0.597
  comGA/cglA/cilD Streptococcus pneumoniae D39

60.129

99.361

0.597
  comGA/cglA/cilD Streptococcus pneumoniae R6

60.129

99.361

0.597
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

60.129

99.361

0.597
  comGA Lactococcus lactis subsp. cremoris KW2

52.09

99.361

0.518
  comGA Latilactobacillus sakei subsp. sakei 23K

38.908

93.61

0.364