Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   I6H74_RS07145 Genome accession   NZ_CP066069
Coordinates   1458549..1459223 (-) Length   224 a.a.
NCBI ID   WP_003060678.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1453549..1464223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS07120 (I6H74_07115) - 1453734..1455011 (-) 1278 WP_015017041.1 pyrimidine-nucleoside phosphorylase -
  I6H74_RS07125 (I6H74_07120) - 1454998..1455597 (-) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  I6H74_RS07130 (I6H74_07125) coaA 1455866..1456786 (+) 921 WP_012766986.1 type I pantothenate kinase -
  I6H74_RS07135 (I6H74_07130) rpsT 1456840..1457088 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  I6H74_RS07140 (I6H74_07135) ciaH 1457246..1458556 (-) 1311 WP_012766987.1 HAMP domain-containing sensor histidine kinase Regulator
  I6H74_RS07145 (I6H74_07140) ciaR 1458549..1459223 (-) 675 WP_003060678.1 response regulator transcription factor Regulator
  I6H74_RS07150 (I6H74_07145) - 1459427..1461964 (-) 2538 WP_115256876.1 M1 family metallopeptidase -
  I6H74_RS07155 (I6H74_07150) phoU 1462165..1462818 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -
  I6H74_RS07160 (I6H74_07155) pstB 1462896..1463654 (-) 759 WP_115256875.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25601.58 Da        Isoelectric Point: 4.4684

>NTDB_id=453571 I6H74_RS07145 WP_003060678.1 1458549..1459223(-) (ciaR) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGQKEVQVDGRPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVDKLQTLRSVGYILKSHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=453571 I6H74_RS07145 WP_003060678.1 1458549..1459223(-) (ciaR) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGCTGATTATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACATGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACAGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAATGTCGTAG
TGGATTTAGGGCAAAAAGAAGTTCAAGTGGATGGCCGGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTGTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATTTTGTGGACAAACTGCAGACATTGA
GAAGCGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(5-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae D39

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae R6

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae TIGR4

84.615

98.661

0.835
  ciaR Streptococcus mutans UA159

84.163

98.661

0.83
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.326

100

0.388
  vicR Streptococcus mutans UA159

35.443

100

0.375