Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   I6H74_RS07140 Genome accession   NZ_CP066069
Coordinates   1457246..1458556 (-) Length   436 a.a.
NCBI ID   WP_012766987.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1452246..1463556
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS07110 (I6H74_07105) - 1452680..1453069 (-) 390 WP_003058840.1 cytidine deaminase -
  I6H74_RS07115 (I6H74_07110) deoC 1453056..1453718 (-) 663 WP_003058850.1 deoxyribose-phosphate aldolase -
  I6H74_RS07120 (I6H74_07115) - 1453734..1455011 (-) 1278 WP_015017041.1 pyrimidine-nucleoside phosphorylase -
  I6H74_RS07125 (I6H74_07120) - 1454998..1455597 (-) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  I6H74_RS07130 (I6H74_07125) coaA 1455866..1456786 (+) 921 WP_012766986.1 type I pantothenate kinase -
  I6H74_RS07135 (I6H74_07130) rpsT 1456840..1457088 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  I6H74_RS07140 (I6H74_07135) ciaH 1457246..1458556 (-) 1311 WP_012766987.1 HAMP domain-containing sensor histidine kinase Regulator
  I6H74_RS07145 (I6H74_07140) ciaR 1458549..1459223 (-) 675 WP_003060678.1 response regulator transcription factor Regulator
  I6H74_RS07150 (I6H74_07145) - 1459427..1461964 (-) 2538 WP_115256876.1 M1 family metallopeptidase -
  I6H74_RS07155 (I6H74_07150) phoU 1462165..1462818 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49917.46 Da        Isoelectric Point: 8.2375

>NTDB_id=453570 I6H74_RS07140 WP_012766987.1 1457246..1458556(-) (ciaH) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MNKLKKEVFSDQYNHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLINFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=453570 I6H74_RS07140 WP_012766987.1 1457246..1458556(-) (ciaH) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATACAACCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTCCTTTGATGCTTTCTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACTACTAGCCTGATTAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATTAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGCCGAAAGCCGATTTTGG
AAAGTTATGAAAAACAAAAAATGTTTGTGGAAAATGCTAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCTCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCAAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGATGATGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGGCCTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.124

100

0.583
  ciaH Streptococcus pneumoniae Rx1

51.37

100

0.516
  ciaH Streptococcus pneumoniae D39

51.37

100

0.516
  ciaH Streptococcus pneumoniae R6

51.37

100

0.516
  ciaH Streptococcus pneumoniae TIGR4

51.37

100

0.516