Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   HSZ52_RS07875 Genome accession   NZ_CP054440
Coordinates   1598761..1599636 (-) Length   291 a.a.
NCBI ID   WP_011303269.1    Uniprot ID   Q49X34
Organism   Staphylococcus saprophyticus strain UTI-058y     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1594020..1617272 1598761..1599636 within 0


Gene organization within MGE regions


Location: 1594020..1617272
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSZ52_RS07860 (HSZ52_07860) xerC 1594020..1594910 (-) 891 WP_011303266.1 tyrosine recombinase XerC -
  HSZ52_RS07865 (HSZ52_07865) trmFO 1595029..1596336 (-) 1308 WP_047503612.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  HSZ52_RS07870 (HSZ52_07870) topA 1596491..1598557 (-) 2067 WP_011303268.1 type I DNA topoisomerase -
  HSZ52_RS07875 (HSZ52_07875) dprA 1598761..1599636 (-) 876 WP_011303269.1 DNA-processing protein DprA Machinery gene
  HSZ52_RS07880 (HSZ52_07880) sucD 1599943..1600848 (-) 906 WP_011303270.1 succinate--CoA ligase subunit alpha -
  HSZ52_RS07885 (HSZ52_07885) sucC 1600870..1602036 (-) 1167 WP_011303271.1 ADP-forming succinate--CoA ligase subunit beta -
  HSZ52_RS07890 (HSZ52_07890) - 1602144..1602914 (-) 771 WP_047503601.1 ribonuclease HII -
  HSZ52_RS07895 (HSZ52_07895) ylqF 1602921..1603781 (-) 861 WP_047503598.1 ribosome biogenesis GTPase YlqF -
  HSZ52_RS07900 (HSZ52_07900) - 1604149..1606728 (+) 2580 WP_047503595.1 YfhO family protein -
  HSZ52_RS07905 (HSZ52_07905) - 1606771..1609392 (+) 2622 WP_048787217.1 YfhO family protein -
  HSZ52_RS07910 (HSZ52_07910) rplS 1609531..1609881 (-) 351 WP_002483481.1 50S ribosomal protein L19 -
  HSZ52_RS07915 (HSZ52_07915) trmD 1609985..1610722 (-) 738 WP_002483482.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  HSZ52_RS07920 (HSZ52_07920) rimM 1610722..1611228 (-) 507 WP_002483483.1 ribosome maturation factor RimM -
  HSZ52_RS07925 (HSZ52_07925) rpsP 1611454..1611720 (-) 267 WP_002483484.1 30S ribosomal protein S16 -
  HSZ52_RS07930 (HSZ52_07930) - 1612139..1612891 (+) 753 WP_011303277.1 3-oxoacyl-ACP reductase -
  HSZ52_RS07935 (HSZ52_07935) - 1612913..1614211 (+) 1299 WP_061050612.1 LLM class flavin-dependent oxidoreductase -
  HSZ52_RS07940 (HSZ52_07940) ffh 1614337..1615704 (-) 1368 WP_011303279.1 signal recognition particle protein -
  HSZ52_RS07945 (HSZ52_07945) - 1615733..1616065 (-) 333 WP_011303280.1 putative DNA-binding protein -
  HSZ52_RS07950 (HSZ52_07950) ftsY 1616052..1617272 (-) 1221 WP_011303281.1 signal recognition particle-docking protein FtsY -

Sequence

Protein


Download         Length: 291 a.a.        Molecular weight: 33710.41 Da        Isoelectric Point: 10.3610

>NTDB_id=452539 HSZ52_RS07875 WP_011303269.1 1598761..1599636(-) (dprA) [Staphylococcus saprophyticus strain UTI-058y]
MNDLDLLKLRFAGLSTQQIHRLLRFSPSFMKYSKVDKQYILKQFLGTVKITAKNENVYRLYVTTNLEVLFKQLKAWKVHF
ITINHRLYPQLLREIYDPPLILFYRGKLTLMQSPRTLAIIGSRQATQYTWQSLQTFFPSFKKHHLTIISGLAKGADMMAH
QHALLFKLPTIAVLGFGHMHHYPKETKEIRQQIEKDGIVISEYLPLEKPKRYHFPERNRLISGLSKGIFITESAENSGTS
ITTRFALEQNRDVYVLPGTIFNKMTLGNLRSAQEGAKIVLNADDILEDFII

Nucleotide


Download         Length: 876 bp        

>NTDB_id=452539 HSZ52_RS07875 WP_011303269.1 1598761..1599636(-) (dprA) [Staphylococcus saprophyticus strain UTI-058y]
ATGAACGATTTAGACCTTTTAAAGCTTCGATTTGCTGGACTATCTACACAACAAATACATCGATTATTAAGATTTTCTCC
CTCTTTTATGAAATATAGTAAGGTAGATAAACAATACATACTCAAACAATTTTTGGGAACAGTAAAAATAACTGCAAAAA
ATGAAAATGTATACCGATTATATGTGACAACTAATTTAGAAGTACTATTCAAACAATTAAAAGCATGGAAAGTTCATTTC
ATAACAATTAATCACCGTTTATATCCACAGTTATTGCGAGAAATTTATGATCCACCCCTAATCCTATTTTATCGCGGTAA
GCTCACTTTAATGCAATCTCCTCGTACCCTAGCTATTATTGGATCTAGACAAGCGACACAATATACATGGCAATCACTTC
AAACATTTTTTCCTTCATTTAAAAAACATCATTTGACGATAATATCAGGGCTTGCAAAAGGTGCAGATATGATGGCGCAT
CAACATGCTTTGTTATTTAAGTTACCTACAATTGCGGTATTAGGATTTGGACATATGCATCATTATCCGAAAGAAACTAA
AGAGATAAGACAGCAAATTGAAAAAGATGGAATAGTTATAAGTGAATATCTCCCTCTCGAAAAGCCCAAAAGATACCATT
TCCCAGAAAGGAATAGATTGATTAGTGGACTTTCTAAAGGTATCTTTATCACAGAATCTGCAGAAAATAGTGGTACAAGT
ATCACGACGCGATTTGCATTAGAACAAAATAGAGATGTGTATGTCTTACCTGGTACAATATTTAATAAAATGACATTAGG
CAATTTGCGTAGTGCTCAAGAAGGGGCGAAAATTGTATTGAATGCGGATGATATATTAGAAGATTTTATTATATGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(74-280)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q49X34

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

50.338

100

0.512
  dprA Staphylococcus aureus N315

50.338

100

0.512
  dprA Lactococcus lactis subsp. cremoris KW2

38.966

99.656

0.388
  dprA Vibrio campbellii strain DS40M4

36.949

100

0.375