Detailed information NTG0451201

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: HRE60_RS09840
• Genome accession: NZ_CP054153
• Coordinates: 2141556..2142791 (+)
• Length: 411 a.a.
• NCBI ID: WP_002883958.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain DB-B5
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2136556..2147791

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HRE60_RS09810 (HRE60_09810)	-	2137029..2139623 (+)	2595	WP_181670822.1	YfhO family protein	-
HRE60_RS09830 (HRE60_09830)	-	2140172..2140855 (-)	684	WP_013991345.1	YoaK family protein	-
HRE60_RS09835 (HRE60_09835)	rlmH	2140871..2141350 (-)	480	WP_002887123.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
HRE60_RS09840 (HRE60_09840)	htrA	2141556..2142791 (+)	1236	WP_002883958.1	trypsin-like peptidase domain-containing protein	Regulator
HRE60_RS09845 (HRE60_09845)	spo0J	2142858..2143625 (+)	768	WP_038676938.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42931.09 Da
• Isoelectric Point: 4.6266

>NTDB_id=451201 HRE60_RS09840 WP_002883958.1 2141556..2142791(+) (htrA) [Streptococcus salivarius strain DB-B5]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNSTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSSQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDDVKSGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide

• Length: 1236 bp

>NTDB_id=451201 HRE60_RS09840 WP_002883958.1 2141556..2142791(+) (htrA) [Streptococcus salivarius strain DB-B5]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCAATTGCAATGCTTGTTATTGGCTTGCTAGGTGGTTTGCTAGGTGC
CTTTATCCTACTAACAGCAGCAGGGGTATCTTTTACCAATTCAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ATAATACAACAGATACAACTAAAGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTACCAAGAAGGGTCA
TCTTCAGATTCTCTAAATGAACTTTATGGCCGTATCTTTGGTGGAGATGATAGTTCTGACTCTAGCCAAGACAAATCAAA
AGATTCTGATGGGTTACAAGTCGCTGGTGAAGGTTCCGGTGTTATCTATAAAAAGGATGGTAAAGAGGCTTATATCGTAA
CCAACAACCACGTTGTCGATGGCGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATTAAAACCGTAGCGGAATTTGCAGACTC
AAACTCTCTCACAGTCGGTGAGAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAGG
GAATCGTTTCTAGCCTTAGCCGTACCGTAACTATGCAAAACGACAATGGTGAAACTGTTTCAACAAATGCTATCCAAACG
GATGCTGCCATTAACCCTGGTAACTCAGGTGGTGCCTTAGTCAATATCGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCAGCAGTCGCTGGCAGCGCCGTTGAAGGTATGGGATTTGCCATTCCATCAAACGATGTTGTCGAAA
TCATCAATCAATTGGAAAAAGACGGTAAAGTCACACGACCAGCCCTAGGAATCTCAATGGCCGATCTTAACAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGATGTGAAATCTGGAGTGGTAGTCGGCAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATCACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CTAATCTATACAGCCATAGTATCGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTGTCTGACTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (307-402)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• Peptidase family M50 (Peptidase_M50) (7-406)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	62.035	98.054	0.608
htrA	Streptococcus gordonii str. Challis substr. CH1	57.389	98.783	0.567
htrA	Streptococcus pneumoniae Rx1	54.523	99.513	0.543
htrA	Streptococcus pneumoniae R6	54.523	99.513	0.543
htrA	Streptococcus pneumoniae TIGR4	54.523	99.513	0.543
htrA	Streptococcus pneumoniae D39	54.523	99.513	0.543
htrA	Streptococcus mitis NCTC 12261	54.523	99.513	0.543