Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   HRE60_RS01310 Genome accession   NZ_CP054153
Coordinates   247921..250017 (+) Length   698 a.a.
NCBI ID   WP_181670914.1    Uniprot ID   A0A7L6WHB2
Organism   Streptococcus salivarius strain DB-B5     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 242921..255017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HRE60_RS01285 (HRE60_01285) trkA 242998..244347 (-) 1350 WP_181670911.1 Trk system potassium transporter TrkA -
  HRE60_RS01290 (HRE60_01290) - 244638..245147 (+) 510 WP_049529100.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  HRE60_RS01295 (HRE60_01295) - 245457..246014 (+) 558 WP_181670912.1 ECF transporter S component -
  HRE60_RS01300 (HRE60_01300) - 246017..246667 (+) 651 WP_002883719.1 phosphatase PAP2 family protein -
  HRE60_RS01305 (HRE60_01305) comR 246847..247746 (+) 900 WP_181670913.1 XRE family transcriptional regulator Regulator
  HRE60_RS01310 (HRE60_01310) comA 247921..250017 (+) 2097 WP_181670914.1 peptide cleavage/export ABC transporter Regulator
  HRE60_RS01315 (HRE60_01315) - 250127..250459 (+) 333 WP_014633880.1 DUF805 domain-containing protein -
  HRE60_RS01320 (HRE60_01320) - 250511..251905 (-) 1395 WP_238799504.1 DUF4153 domain-containing protein -
  HRE60_RS01325 (HRE60_01325) - 252292..253140 (+) 849 WP_002883793.1 amino acid ABC transporter substrate-binding protein -
  HRE60_RS01330 (HRE60_01330) - 253300..254202 (+) 903 WP_073687407.1 MetQ/NlpA family ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78503.59 Da        Isoelectric Point: 9.3517

>NTDB_id=451149 HRE60_RS01310 WP_181670914.1 247921..250017(+) (comA) [Streptococcus salivarius strain DB-B5]
MSKYPYISQVDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQENLSY
PFIAHVVKEGGLQHYYTVFGQIKGKLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGETYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVFSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALILQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAL
KGVSHRFSYQQETLRKVDLMIHKGEKIALMGKSGSGKTTLAKILSGYYTKSSGHVTLDKDIIGHAELRQIVTYVPQQTYV
FTGTILENLLLGFEGGVDEKKLLKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSPNFNPFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=451149 HRE60_RS01310 WP_181670914.1 247921..250017(+) (comA) [Streptococcus salivarius strain DB-B5]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGGGAGTTGGCTCAGACTTCTCGTGAAGGCACTTCTGCGCTTGGTTTGGTTG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCCATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAACCTATCTTAT
CCTTTTATTGCACATGTGGTTAAAGAAGGTGGATTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGAAGCTTGT
TATTGGCGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAGTTTGCTAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAACCTACACTAAATACAAAGAAGATGTGCCTGGGCTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTGTTAAGTTTTCTAGTGACCCTTGTTAATATTATTGGCTCTTATTATTT
GCAATCTATTATTGACCGCTTGATTCCTCAGGAGGCTTACACTCTTCTGACCATGATTTCGCTAGGCCTATGTATCTCTT
ATCTAGCTCAACAAGTATTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGAAATTACTTGTCCATTGCTGTCATT
CTTCCTTATATTAAGCATGTCTTTTCCTTACCTATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATAACGTCACGTTT
TGGCGATGCTAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCTCTTATTTTACAAAATCAGTCACTTTTTGTGATGACTCTCACGGTAGTGCCTCTTTATGTGTTAATCATT
TTGGCCTTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGCATTGAAACCTTAAAATCCTTGAGAGTTGAAGAAAGACGCTATCAGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCCAAGTGGCAATTAACACAGGATGGTTTAAAGACGGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTATGGTATGGGGCACAATTGGTCATGGAAGGACAGCTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTACTGAATTATTTTACAACTCCTTTAATTAATATTATCAATCTCCAATCCAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGATAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCCTTTAAACAACTTGCTCTT
AAGGGTGTCAGTCACCGTTTTAGTTATCAGCAAGAGACGCTTAGAAAGGTTGATTTAATGATTCATAAGGGGGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGGAAAACGACCTTGGCTAAAATATTGTCGGGTTATTACACAAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATATTATTGGCCATGCGGAGCTGCGTCAAATAGTGACTTACGTTCCCCAGCAGACCTATGTA
TTTACCGGAACCATTTTAGAAAATCTGCTATTAGGATTTGAGGGAGGAGTTGACGAGAAAAAGCTTCTTAAAGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGTTTTCAGACCCAAGTATCTGAAGATGGTGGTCTATCTG
GTGGTCAAAAACAACGCTTGGCGATAGCGAGGGCCCTCTTGTCCAAGCAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTCCGTCAACATGTCAGTCGTGTGGTGACCATGGTGAGTGGCCAGATTGAGTCAGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-139)

ABC transporter transmembrane region (ABC_membrane)

(167-436)

ABC transporter (ABC_tran)

(494-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L6WHB2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

53.69

98.997

0.532
  comA Streptococcus gordonii str. Challis substr. CH1

53.161

99.713

0.53
  comA Streptococcus mitis NCTC 12261

53.401

98.997

0.529
  comA Streptococcus pneumoniae Rx1

53.111

98.997

0.526
  comA Streptococcus pneumoniae D39

53.111

98.997

0.526
  comA Streptococcus pneumoniae R6

53.111

98.997

0.526
  comA Streptococcus pneumoniae TIGR4

52.967

98.997

0.524
  comA/nlmT Streptococcus mutans UA159

50.29

98.854

0.497