Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   FOC63_RS07540 Genome accession   NZ_CP054015
Coordinates   1467774..1468439 (+) Length   221 a.a.
NCBI ID   WP_009853767.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain FDAARGOS_755     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1462774..1473439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC63_RS07520 (FOC63_07520) - 1464193..1465773 (+) 1581 WP_009853763.1 DEAD/DEAH box helicase -
  FOC63_RS07525 (FOC63_07525) - 1465817..1466089 (-) 273 WP_009853764.1 GIY-YIG nuclease family protein -
  FOC63_RS07530 (FOC63_07530) - 1466064..1466825 (-) 762 WP_009853765.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  FOC63_RS07535 (FOC63_07535) - 1466933..1467679 (+) 747 WP_009853766.1 lysophospholipid acyltransferase family protein -
  FOC63_RS07540 (FOC63_07540) comEA 1467774..1468439 (+) 666 WP_009853767.1 helix-hairpin-helix domain-containing protein Machinery gene
  FOC63_RS07545 (FOC63_07545) comEC/celB 1468432..1470663 (+) 2232 WP_043878536.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FOC63_RS07550 (FOC63_07550) holA 1470737..1471774 (+) 1038 WP_009853769.1 DNA polymerase III subunit delta -
  FOC63_RS07555 (FOC63_07555) sodA 1471863..1472471 (+) 609 WP_014619989.1 superoxide dismutase SodA -
  FOC63_RS07560 (FOC63_07560) - 1472623..1473348 (+) 726 WP_012961667.1 YebC/PmpR family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23431.12 Da        Isoelectric Point: 4.3235

>NTDB_id=450165 FOC63_RS07540 WP_009853767.1 1467774..1468439(+) (comEA) [Streptococcus gallolyticus strain FDAARGOS_755]
MIEEIKEKLLENKTLVAVLGTILVMLIGFFAWSNVTKTTVDAQSDLPALSTTFSASSSASDLKTERSSSQTETQKVFVDI
KGAVKNEGVYELSSGSRVTDVVKLAGGFTEDADKKSVNLAEKVTDEAVIYVARVGENVAPATTNSQANGSAQQEESSDKI
NLNTATLAELQTISGIGAKRAQDIIDYRDANGGFSSVDDLANVSGIGEKTLEKLKSEVTVD

Nucleotide


Download         Length: 666 bp        

>NTDB_id=450165 FOC63_RS07540 WP_009853767.1 1467774..1468439(+) (comEA) [Streptococcus gallolyticus strain FDAARGOS_755]
ATGATTGAAGAAATAAAAGAAAAACTTTTGGAGAACAAAACGTTGGTAGCGGTGTTGGGAACAATACTTGTTATGTTAAT
CGGATTTTTTGCTTGGTCAAATGTGACAAAAACAACAGTGGATGCGCAAAGTGACCTACCTGCCCTAAGCACGACTTTTT
CGGCAAGTAGCAGCGCAAGTGATTTAAAAACAGAACGTTCAAGTTCGCAAACTGAAACTCAAAAAGTGTTTGTAGATATC
AAAGGCGCTGTGAAAAATGAGGGTGTTTATGAGCTTTCAAGCGGTAGCCGTGTGACAGATGTGGTCAAATTAGCAGGTGG
TTTTACAGAAGATGCTGATAAGAAGTCGGTGAATTTGGCTGAAAAAGTAACCGATGAAGCGGTGATTTATGTGGCAAGAG
TTGGTGAAAATGTTGCTCCTGCAACGACTAATTCACAAGCAAATGGCAGCGCTCAACAGGAAGAAAGTTCAGATAAAATC
AATCTTAATACCGCAACTTTGGCGGAACTCCAGACGATTTCTGGCATTGGCGCCAAACGTGCCCAAGACATTATTGACTA
CCGTGATGCCAATGGTGGTTTTTCATCAGTTGATGACTTGGCGAATGTGTCTGGTATCGGAGAAAAAACACTAGAAAAGC
TAAAATCTGAGGTGACCGTTGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(157-219)

SLBB domain (SLBB)

(78-131)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

48.498

100

0.511
  comEA/celA/cilE Streptococcus mitis SK321

47.964

100

0.48
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

46.637

100

0.471
  comEA/celA/cilE Streptococcus pneumoniae Rx1

45.74

100

0.462
  comEA/celA/cilE Streptococcus pneumoniae D39

45.74

100

0.462
  comEA/celA/cilE Streptococcus pneumoniae R6

45.74

100

0.462
  comEA/celA/cilE Streptococcus mitis NCTC 12261

45.291

100

0.457
  comEA Latilactobacillus sakei subsp. sakei 23K

38.117

100

0.385
  comEA Staphylococcus aureus MW2

36.364

99.548

0.362