Detailed information NTG0450138

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: FOC63_RS04265
• Genome accession: NZ_CP054015
• Coordinates: 855706..856605 (+)
• Length: 299 a.a.
• NCBI ID: WP_009853198.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus strain FDAARGOS_755
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 850706..861605

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC63_RS04240 (FOC63_04240)	-	850905..851354 (+)	450	WP_009853193.1	DUF523 domain-containing protein	-
FOC63_RS04245 (FOC63_04245)	purE	851354..851842 (+)	489	WP_009853194.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
FOC63_RS04250 (FOC63_04250)	purK	851829..852902 (+)	1074	WP_009853195.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
FOC63_RS04255 (FOC63_04255)	-	852913..853959 (+)	1047	WP_014619874.1	hypothetical protein	-
FOC63_RS04260 (FOC63_04260)	purB	854261..855559 (+)	1299	WP_009853197.1	adenylosuccinate lyase	-
FOC63_RS04265 (FOC63_04265)	comR	855706..856605 (+)	900	WP_009853198.1	helix-turn-helix domain-containing protein	Regulator
FOC63_RS04270 (FOC63_04270)	-	857847..858278 (+)	432	WP_009853200.1	low molecular weight protein-tyrosine-phosphatase	-
FOC63_RS04275 (FOC63_04275)	-	858298..858678 (+)	381	WP_009853201.1	membrane protein	-
FOC63_RS04280 (FOC63_04280)	-	858675..860468 (+)	1794	WP_009853202.1	acyltransferase family protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 34967.15 Da
• Isoelectric Point: 5.1732

>NTDB_id=450138 FOC63_RS04265 WP_009853198.1 855706..856605(+) (comR) [Streptococcus gallolyticus strain FDAARGOS_755]
MEKFGIKVRALREKKGISREEFCGDETELSVRQLARIEKGQSVPTLNKVGYIAKVLGVTIGELTDGKNLELPTRYKELKY
LLLRTPTYGDKERLKRQTSYFDEISEKYYEVIPEEERLIIDCLQSKIDVHFSDDVNFGEGILNDYFDQVRRKKNFQINDL
ILIDLYFACLASAKSFVGIYSLDLYDELMECLLNQENLSPETSLILNNVLLNNVDLVLRFHRESFMKRIIIKSDTIMTSV
HDFQRRPVLSLVEWKYYLQFKKDFLAAQKSYSNAILFANLIGDTYLENKLIEEWNNDTT

Nucleotide

• Length: 900 bp

>NTDB_id=450138 FOC63_RS04265 WP_009853198.1 855706..856605(+) (comR) [Streptococcus gallolyticus strain FDAARGOS_755]
TTGGAAAAGTTTGGGATTAAAGTACGTGCATTAAGAGAGAAAAAAGGGATTTCACGTGAAGAATTCTGTGGTGATGAAAC
AGAATTATCTGTGAGACAGCTAGCTAGAATTGAAAAAGGACAATCCGTCCCAACTCTTAATAAGGTGGGATATATTGCAA
AAGTATTAGGAGTAACTATTGGTGAGTTAACTGATGGTAAAAATTTAGAACTTCCCACTCGGTATAAGGAGTTAAAATAT
TTACTATTACGAACACCAACTTATGGGGATAAGGAACGTCTTAAGAGACAAACTTCATATTTTGATGAAATTTCAGAAAA
ATACTATGAAGTTATACCTGAAGAAGAACGCTTAATTATTGATTGTTTACAATCGAAGATTGATGTTCATTTTAGTGATG
ATGTTAATTTTGGTGAAGGAATTTTAAATGATTATTTTGACCAAGTTAGACGAAAGAAGAACTTTCAAATTAATGATTTG
ATTTTAATAGATTTATATTTTGCTTGCCTTGCTTCTGCTAAATCGTTTGTGGGAATCTATAGCTTAGATTTGTATGATGA
ATTAATGGAGTGTTTACTAAATCAAGAAAATCTTTCACCAGAAACTTCTTTGATTTTAAATAATGTTTTGTTAAATAATG
TAGATTTGGTTTTACGATTCCATAGAGAATCTTTTATGAAACGAATTATTATAAAAAGTGACACTATCATGACAAGTGTT
CATGATTTTCAAAGACGTCCAGTTTTAAGTTTAGTTGAGTGGAAATATTATTTACAATTTAAAAAAGATTTTTTAGCGGC
ACAAAAATCTTACTCCAATGCTATTTTATTTGCTAACTTAATTGGAGATACTTATTTGGAAAATAAGTTAATAGAAGAAT
GGAATAATGACACAACATGA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (8-63)

• ComR tetratricopeptide (ComR_TPR) (72-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	72.474	95.987	0.696
comR	Streptococcus mutans UA159	54.515	100	0.545
comR	Streptococcus pyogenes MGAS8232	49.333	100	0.495
comR	Streptococcus pyogenes MGAS315	47.315	99.666	0.472
comR	Streptococcus suis P1/7	39.799	100	0.398
comR	Streptococcus suis 05ZYH33	39.799	100	0.398
comR	Streptococcus suis D9	37.71	99.331	0.375