Detailed information NTG0450014

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: FOC71_RS04945
• Genome accession: NZ_CP053999
• Coordinates: 949491..951641 (+)
• Length: 716 a.a.
• NCBI ID: WP_003073366.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain FDAARGOS_769
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 944491..956641

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC71_RS04915 (FOC71_04915)	pyrH	944522..945262 (+)	741	WP_003073377.1	UMP kinase	-
FOC71_RS04920 (FOC71_04920)	frr	945266..945823 (+)	558	WP_003069936.1	ribosome recycling factor	-
FOC71_RS04925 (FOC71_04925)	cvfB	945936..946790 (+)	855	WP_003073375.1	RNA-binding virulence regulatory protein CvfB	-
FOC71_RS04930 (FOC71_04930)	holA	946850..947887 (+)	1038	WP_003073373.1	DNA polymerase III subunit delta	-
FOC71_RS04935 (FOC71_04935)	-	947958..948563 (+)	606	WP_003073371.1	superoxide dismutase	-
FOC71_RS04940 (FOC71_04940)	-	948636..949010 (-)	375	WP_003073369.1	hypothetical protein	-
FOC71_RS04945 (FOC71_04945)	comA/nlmT	949491..951641 (+)	2151	WP_003073366.1	peptide cleavage/export ABC transporter	Regulator
FOC71_RS04950 (FOC71_04950)	-	951652..953013 (+)	1362	WP_003073364.1	bacteriocin secretion accessory protein	-
FOC71_RS04955 (FOC71_04955)	-	953110..953262 (+)	153	WP_003073362.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
FOC71_RS04960 (FOC71_04960)	-	953343..954659 (-)	1317	WP_003073361.1	sensor histidine kinase	-
FOC71_RS04965 (FOC71_04965)	comE/blpR	954661..955407 (-)	747	WP_037584574.1	response regulator transcription factor	Regulator
FOC71_RS04970 (FOC71_04970)	-	955576..956289 (-)	714	WP_003073356.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 80427.07 Da
• Isoelectric Point: 9.3439

>NTDB_id=450014 FOC71_RS04945 WP_003073366.1 949491..951641(+) (comA/nlmT) [Streptococcus intermedius strain FDAARGOS_769]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKGKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKEIFATEWTGVAIFLAPEPSYKPHKDKKNGLISLIPLI
FKQKMLVTYIVLASLLVTLINIVGSYYLQGILDEYIPNQMRSTLGIVSIGLILTYILQQMMSFSRDYLLIVLSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLSILIIVGGVLLLQNTNLFFLTLLAIPIYTVI
IFAFIKPFEKMNHDVMQSNSMVNSAIIEDINGIETIKSLTSEEARYQKIDSEFVNYLDKSFTLSKYSIFQTTLKQGFQLI
LNVLILWLGAHLVISEKISIGQLITFTALLSYFTNSLESIINLQTKLQSAKVANKRLNEVYLVESEFKTKQTLTEKGFLA
GDITFHNVSYKYGFGRDTLSDINLTIKTGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFSGSILENLTLGMNQIFSQKEIIRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGSHAELMERQGFYHHLFNK

Nucleotide

• Length: 2151 bp

>NTDB_id=450014 FOC71_RS04945 WP_003073366.1 949491..951641(+) (comA/nlmT) [Streptococcus intermedius strain FDAARGOS_769]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTTGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCGCAAGAAATAGGTTTTGAGACACGACCGATTCAAGGGGATATGTCTTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGGTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGACCCAAGTGTAAAAATAACCAAGATCTCAAAAGAAATATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAACCACATAAGGATAAGAAAAATGGTTTGATAAGCTTAATTCCTCTTATT
TTTAAACAGAAAATGCTGGTCACCTATATTGTTTTAGCTAGTCTGCTTGTGACACTCATCAATATTGTTGGATCTTACTA
CCTACAAGGAATTTTAGACGAATACATTCCAAATCAAATGAGATCAACTCTTGGAATAGTGTCTATTGGTCTGATTCTTA
CTTATATTTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTGTACTTAGTCAGCGGCTGACCATCGATGTG
ATTTTATCATATATTCGACATATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTCTATTTTGATAA
TAGTAGGAGGGGTATTATTATTACAGAATACCAACCTTTTCTTCCTCACTCTGCTTGCTATTCCTATCTATACGGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATCATGACGTCATGCAAAGCAATTCCATGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACCATTAAATCTTTAACAAGCGAAGAAGCCCGTTACCAAAAGATAGACAGCGAATTTG
TAAATTATTTAGATAAATCTTTTACGCTTAGTAAATATTCTATTTTTCAAACAACTCTTAAACAAGGCTTTCAATTAATT
TTAAATGTGCTTATTTTATGGCTCGGTGCGCATTTAGTTATATCTGAGAAAATCTCAATTGGGCAGCTCATCACATTTAC
GGCTCTACTTTCTTATTTTACAAATTCTCTTGAAAGTATTATTAATCTGCAAACTAAGCTGCAGTCGGCTAAGGTTGCTA
ACAAGCGGTTGAATGAAGTTTATTTAGTAGAGTCTGAATTTAAAACTAAGCAAACACTTACAGAGAAAGGTTTCTTGGCT
GGTGATATTACGTTCCATAATGTCTCCTATAAATACGGCTTTGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AACAGGAGATAAGGTGAGCTTAGTCGGCATCAGTGGTTCGGGAAAGACAACACTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTCAATGGAAATGACCTTAAAATGATTGATAAGAAGACGCTTCGTCAATATATCAAT
TATTTACCACAACAAGCCTATATTTTTAGTGGTTCTATCTTAGAAAATCTTACATTAGGGATGAATCAAATATTTTCTCA
AAAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATGCCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAACGAATTGCTCTAGCACGCGCCCTCTTAACAAAGTCACCAATT
CTTATTCTTGACGAAGCAACGAGCGGATTGGATGTTCTAACTGAGAAAAAGGTCATTGACAATCTGATGGGTTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGGACAAATCAGGTTATTGTTCTTGATAAAGGGCAGA
TTATTGAAACTGGATCCCACGCTGAATTGATGGAAAGACAAGGCTTTTATCATCATTTATTTAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (499-648)

• Peptidase C39 family (Peptidase_C39) (6-141)

• ABC transporter transmembrane region (ABC_membrane) (168-437)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.932	99.022	0.712
comA	Streptococcus mitis NCTC 12261	66.62	99.581	0.663
comA	Streptococcus mitis SK321	66.48	99.581	0.662
comA	Streptococcus gordonii str. Challis substr. CH1	66.059	99.581	0.658
comA	Streptococcus pneumoniae D39	65.919	99.581	0.656
comA	Streptococcus pneumoniae R6	65.919	99.581	0.656
comA	Streptococcus pneumoniae Rx1	65.919	99.581	0.656
comA	Streptococcus pneumoniae TIGR4	65.498	99.581	0.652