Detailed information NTG0044869

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: GGS_RS00675
• Genome accession: NC_018712
• Coordinates: 116941..117381 (+)
• Length: 146 a.a.
• NCBI ID: WP_003061780.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis RE378
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 111941..122381

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GGS_RS00645 (GGS_0124)	-	113622..113987 (+)	366	WP_003055257.1	DUF1033 family protein	-
GGS_RS00650 (GGS_0125)	comGA/cglA	114068..115009 (+)	942	WP_015016543.1	competence type IV pilus ATPase ComGA	Machinery gene
GGS_RS00655 (GGS_0126)	comGB	114945..115976 (+)	1032	WP_042357807.1	competence type IV pilus assembly protein ComGB	Machinery gene
GGS_RS00660 (GGS_0127)	comGC	115978..116304 (+)	327	WP_003055259.1	competence type IV pilus major pilin ComGC	Machinery gene
GGS_RS00665 (GGS_0128)	comGD	116279..116707 (+)	429	WP_041788719.1	competence type IV pilus minor pilin ComGD	Machinery gene
GGS_RS00670 (GGS_0129)	comGE	116715..116960 (+)	246	WP_003058569.1	competence type IV pilus minor pilin ComGE	Machinery gene
GGS_RS00675 (GGS_0130)	comGF	116941..117381 (+)	441	WP_003061780.1	competence type IV pilus minor pilin ComGF	Machinery gene
GGS_RS00680 (GGS_0131)	comGG	117410..117733 (+)	324	WP_227985720.1	competence type IV pilus minor pilin ComGG	-
GGS_RS00685 (GGS_0132)	comGH	117796..118749 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
GGS_RS00690 (GGS_0133)	-	118808..120004 (+)	1197	WP_003058485.1	acetate kinase	-
GGS_RS00695	-	120310..120516 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
GGS_RS00700 (GGS_0134)	-	120619..121299 (+)	681	WP_003060329.1	type II CAAX endopeptidase family protein	-
GGS_RS00705 (GGS_0135)	-	121317..121754 (+)	438	WP_012766452.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16969.55 Da
• Isoelectric Point: 10.6305

>NTDB_id=44869 GGS_RS00675 WP_003061780.1 116941..117381(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis RE378]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWLLFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=44869 GGS_RS00675 WP_003061780.1 116941..117381(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis RE378]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTACTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAGAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	48.921	95.205	0.466
comGF	Streptococcus mutans UA140	48.201	95.205	0.459
comGF	Lactococcus lactis subsp. cremoris KW2	46.377	94.521	0.438
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae R6	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae TIGR4	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae D39	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae Rx1	43.796	93.836	0.411