Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   STMM20_RS03180 Genome accession   NZ_CP065485
Coordinates   604802..606673 (+) Length   623 a.a.
NCBI ID   WP_347103624.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain MM20     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 599802..611673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STMM20_RS03165 (STMM20_03160) fmt 601774..602709 (+) 936 WP_014608534.1 methionyl-tRNA formyltransferase -
  STMM20_RS03170 (STMM20_03165) rsmB 602699..604021 (+) 1323 WP_347103623.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  STMM20_RS03175 (STMM20_03170) - 604065..604802 (+) 738 WP_014727615.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  STMM20_RS03180 (STMM20_03175) stkP/pknB 604802..606673 (+) 1872 WP_347103624.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  STMM20_RS03185 - 607311..607478 (+) 168 WP_014608530.1 potassium channel family protein -
  STMM20_RS03190 (STMM20_03185) liaF 607733..608431 (+) 699 WP_014621793.1 cell wall-active antibiotics response protein LiaF -
  STMM20_RS03195 (STMM20_03190) - 608428..609438 (+) 1011 WP_011226288.1 sensor histidine kinase -
  STMM20_RS03200 (STMM20_03195) vraR 609428..610072 (+) 645 WP_002951384.1 response regulator transcription factor Regulator
  STMM20_RS03215 (STMM20_03210) rimM 610744..611262 (+) 519 WP_011226286.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 67909.80 Da        Isoelectric Point: 6.9480

>NTDB_id=448214 STMM20_RS03180 WP_347103624.1 604802..606673(+) (stkP/pknB) [Streptococcus thermophilus strain MM20]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNESVAIKVLRTNYQTDQVAVARFQREARAMTELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKFIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPFDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLATSLHPSHSRDSKVVFDDMTDTKTLPKVDSVPSVGPEKKISPKPSEPTPAP
SKQPREKASLSKKKKNLFLTLLKVLLGFVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKLESAGFKVGDVKEVEND
SVNKGKVIKTDPTAGTMRKEGASIDVYVSSGSKGFTLKNYKGKNYKDAIEDLTSNYGVSEDQIDIQHLEDDNAKEGEILS
QSPEKNKSFNPKDSKAKIKFRVATPKTITMPDVTGLTVSTAVQTLNSKDISSSSIEYHDYNTGVKLDKSKVPSNTEVLYQ
DPQVGTAVDGTVILYVSVVTKSSSIQQSSSASTTQSSSSTSSSSESSTASSTETATEATHTEQ

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=448214 STMM20_RS03180 WP_347103624.1 604802..606673(+) (stkP/pknB) [Streptococcus thermophilus strain MM20]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGTGTAGCTATTAAGGTGCTACGTACCAATTATCAAACTGATCAGGTTG
CTGTGGCGCGTTTCCAGCGTGAAGCACGTGCCATGACTGAGCTTAGCCATCCGAATATCGTTGCGATTAGAGATATTGGT
GAAGAAGACGGTCAGCAGTTCTTGGTGATGGAGTATGTGGATGGTTCGGACTTGAAGAAATTCATTCAAGACCATGCACC
ATTGTCTAACCAAGATGTTGTGCGTATTATGGGGGAAGTCCTTTCCGCCATGACTCTTGCCCACCAAAAGGGTATTATTC
ACCGTGACCTTAAGCCACAGAACGTTCTATTAACTAAGGATGGTAGAGCTAAGGTTACAGACTTTGGTATCGCAGTAGCA
TTTGCTGAAACCAGCCTGACACAAACTAACTCAATGTTGGGGTCAGTCCATTATTTGTCACCAGAACAGGCACGTGGTTC
TAAAGCCACTATCCAAAGTGATATCTATGCTATGGGGATTATGCTCTTTGAAATGTTGACAGGGCATATCCCTTTTGATG
GCGATAGTGCAGTAACCATTGCACTTCAACATTTCCAAAAGCCCCTGCCATCGATTTTGGCTGAGAACCGTAACGTTCCT
CAAGCTTTAGAAAATGTTGTTATTAGAGCAACTGCTAAAAAGCTTGAAAATCGTTACAACAGCACTTTGGAAATGAGTCG
CGACCTAGCAACTAGTTTGCATCCTAGTCATAGTCGTGATTCTAAGGTAGTTTTTGATGACATGACGGATACTAAGACCC
TGCCAAAGGTCGATTCAGTTCCATCAGTAGGTCCTGAGAAAAAGATTTCTCCTAAACCATCAGAGCCTACACCGGCTCCA
AGCAAACAACCGAGGGAAAAAGCTTCTCTATCTAAAAAAAAGAAAAATCTCTTTTTAACTCTACTCAAGGTTTTACTAGG
CTTCGTCTTTATAGGAATTATCATTTTTGCCTATCTTGTTTTTACCAATCCTGACAATGTCCAAGTACCAAATGTTGTAG
GTCAAGAGTTGTCAACAGCTCAGACGAAACTTGAAAGTGCAGGCTTTAAGGTTGGCGATGTTAAAGAAGTCGAAAATGAT
TCAGTCAATAAGGGCAAAGTTATCAAGACCGACCCTACAGCTGGGACAATGCGTAAAGAGGGAGCAAGCATTGATGTCTA
TGTTTCTTCTGGTAGCAAAGGTTTCACTCTGAAAAATTACAAGGGGAAAAATTATAAGGATGCCATTGAGGATTTAACCT
CGAATTATGGGGTTTCCGAGGATCAGATCGATATTCAACATCTCGAAGACGATAATGCTAAAGAGGGCGAAATTCTATCT
CAAAGTCCGGAGAAAAACAAGTCCTTCAATCCTAAAGATAGTAAGGCAAAAATCAAGTTTCGTGTGGCAACTCCTAAGAC
TATAACTATGCCTGATGTGACTGGTTTAACTGTCTCGACAGCAGTCCAAACCTTGAATAGTAAAGACATTTCAAGTAGCA
GTATTGAGTATCATGACTATAATACTGGTGTTAAGTTGGATAAGAGTAAGGTACCTAGTAATACAGAGGTCCTTTATCAA
GATCCTCAAGTTGGTACTGCTGTTGATGGCACAGTGATTCTCTATGTTTCAGTCGTAACTAAGAGTTCAAGTATTCAACA
GTCAAGCTCAGCAAGTACGACACAATCGTCGTCATCTACAAGTTCTAGTTCTGAAAGTAGTACAGCTTCTAGTACCGAAA
CAGCTACAGAAGCTACTCACACAGAGCAATAA

Domains

Predicted by InterProScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(508-577)

PASTA domain (PASTA)

(436-502)

PASTA domain (PASTA)

(367-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

90.534

93.258

0.844
  pknB Streptococcus mutans UA159

64.706

87.319

0.565
  stkP Streptococcus pneumoniae TIGR4

58.3

79.294

0.462
  stkP Streptococcus pneumoniae D39

58.097

79.294

0.461
  stkP Streptococcus pneumoniae R6

58.097

79.294

0.461
  stkP Streptococcus pneumoniae Rx1

57.895

79.294

0.459